ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2010
Deciphering the contribution of intrinsic and synaptic currents to the effects of transient synaptic inputs on human motor unit discharge.
Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- The effects of membrane potential oscillations on the excitability of rat hypoglossal motoneurons.Frontiers in physiology · 2022Article
- Evidence of two modes of spiking evoked in human firing motoneurones by Ia afferent electrical stimulation.Experimental brain research · 2021Article
- Beta-band motor unit coherence and nonlinear surface EMG features of the first dorsal interosseous muscle vary with force.Journal of neurophysiology · 2019Article
- Transcranial magnetic stimulation induced early silent period and rebound activity re-examined.PloS one · 2019Article
- Spinal inhibition and motor function in adults with spastic cerebral palsy.The Journal of physiology · 2016Article
- Vestibular contribution to balance control in the medial gastrocnemius and soleus.Journal of neurophysiology · 2016Article
- Modulation of motoneuron firing by recurrent inhibition in the adult rat in vivo.Journal of neurophysiology · 2014Article
- Asynchronous recruitment of low-threshold motor units during repetitive, low-current stimulation of the human tibial nerve.Frontiers in human neuroscience · 2014Article
- Analysis of motoneuron responses to composite synaptic volleys (computer simulation study).Experimental brain research · 2012Article
- Estimates of EPSP amplitude based on changes in motoneuron discharge rate and probability.Experimental brain research · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The amplitude and time course of synaptic potentials in human motoneurons can be estimated in tonically discharging motor units by measuring stimulus-evoked changes in the rate and probability of motor unit action potentials. However, in spite of the fact that some of these techniques have been used for over 30 years, there is still no consensus on the best way to estimate the characteristics of synaptic potentials or on the accuracy of these estimates. In this review, we compare different techniques for estimating synaptic potentials from human motor unit discharge and also discuss relevant animal models in which estimated synaptic potentials can be compared to those directly measured from intracellular recordings. We also review the experimental evidence on how synaptic noise and intrinsic motoneuron properties influence their responses to synaptic inputs. Finally, we consider to what extent recordings of single motor unit discharge in humans can be used to distinguish the contribution of changes in synaptic inputs versus changes in intrinsic motoneuron properties to altered motoneuron responses following CNS injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.