Trial reportCritical care (London, England)2010
A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study.
Trial report in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01014299 (Recruitment Maneuver Increases Oxygenation After Intubation in Hypoxemic ICU Patients), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Recruitment Maneuver Increases Oxygenation After Intubation in Hypoxemic ICU Patients: a Randomized Controlled Study
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Heterogeneity of surrogate outcome measures used in critical care studies: A systematic review.Clinical trials (London, England) · 2023Pooled it
- Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials.Critical care (London, England) · 2018Pooled it
- Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation.The Cochrane database of systematic reviews · 2016Pooled it
- Video laryngoscopy versus direct laryngoscopy for orotracheal intubation in the intensive care unit: a systematic review and meta-analysis.Intensive care medicine · 2014Pooled it
- Bedside assessment of the effects of positive end-expiratory pressure on lung inflation and recruitment by the helium dilution technique and electrical impedance tomography.Intensive care medicine · 2016Trial
- Effects of a recruitment maneuver on plasma levels of soluble RAGE in patients with diffuse acute respiratory distress syndrome: a prospective randomized crossover study.Intensive care medicine · 2015Trial
- Non-Invasive Positive Pressure Ventilation for Pre-Oxygenation of Critically Ill Patients Before Intubation.Journal of clinical medicine · 2025Review
- Implementation of a Revised Montpellier Bundle on the Outcome of Intubation in Critically Ill Patients: A Quality Improvement Project.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Effects of Recruitment Maneuvers on Oxygenation and Intracranial Pressure in the Experimental ARDS Model.The Eurasian journal of medicine · 2022Article
- ARDS Clinical Practice Guideline 2021.Journal of intensive care · 2022Article
- Article
- Recent insight into potential acute respiratory distress syndrome.Saudi medical journal · 2017Review
- Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way.World journal of critical care medicine · 2015Review
- Intubation in the ICU: we could improve our practice.Critical care (London, England) · 2014Review
- Review
- Year in review 2010: Critical Care--Respirology.Critical care (London, England) · 2011Review
- Do recruitment maneuvers simply improve oxygenation?Critical care (London, England) · 2010Article
- Noninvasive lung recruitment maneuver prevents reintubation and reduces ICU stay.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTracheal intubation and anaesthesia promotes lung collapse and hypoxemia. In acute lung injury patients, recruitment maneuvers (RMs) increase lung volume and oxygenation, and decrease atelectasis. The aim of this study was to evaluate the efficacy and safety of RMs performed immediately after intubation.
methodsThis randomized controlled study was conducted in two 16-bed medical-surgical intensive care units within the same university hospital. Consecutive patients requiring intubation for acute hypoxemic respiratory failure were included. Patients were randomized to undergo a RM immediately (within 2 minutes) after intubation, consisting of a continuous positive airway pressure (CPAP) of 40 cmH2O over 30 seconds (RM group), or not (control group). Blood gases were sampled and blood samples taken for culture before, within 2 minutes, 5 minutes, and 30 minutes after intubation. Haemodynamic and respiratory parameters were continuously recorded throughout the study. Positive end expiratory pressure (PEEP) was set at 5 cmH2O throughout.
resultsThe control (n = 20) and RM (n = 20) groups were similar in terms of age, disease severity, diagnosis at time of admission, and PaO2 obtained under 10-15 L/min oxygen flow immediately before (81 +/- 15 vs 83 +/- 35 mmHg, P = 0.9), and within 2 minutes after, intubation under 100% FiO2 (81 +/- 15 vs 83 +/- 35 mmHg, P = 0.9). Five minutes after intubation, PaO2 obtained under 100% FiO2 was significantly higher in the RM group compared with the control group (93 +/- 36 vs 236 +/- 117 mmHg, P = 0.008). The difference remained significant at 30 minutes with 110 +/- 39 and 180 +/- 79 mmHg, respectively, for the control and RM groups. No significant difference in haemodynamic conditions was observed between groups at any time. Following tracheal intubation, 15 patients had positive blood cultures, showing microorganisms shared with tracheal aspirates, with no significant difference in the incidence of culture positivity between groups.
conclusionsRecruitment maneuver following intubation in hypoxemic patients improved short-term oxygenation, and was not associated with increased adverse effects.
trial registrationNCT01014299.
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