ArticleBMC cancer2010
Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study.
Article in BMC cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 64 citations in OpenAlex.
- Modeling rare melanoma subtypes: mechanisms, microenvironments and translational opportunities.Frontiers in oncology · 2026Review
- The role of vitamin C in melanoma cell death via activation of cytochrome C and TNF-α protein expression.Scientific reports · 2025Article
- Early termination and nonpublication of phase III/IV melanoma clinical trials: a cross-sectional study.Proceedings (Baylor University. Medical Center) · 2025Article
- Immunohistochemical and transcriptomic characterization of T and myeloid cell infiltrates in canine malignant melanoma.Veterinary and comparative oncology · 2024Article
- Primary malignant melanoma of the stomach: a rare entity.BMJ case reports · 2020Article
- Long-term survival after surgical treatment followed by adjuvant systemic therapy for primary duodenal melanoma.Clinical journal of gastroenterology · 2020Article
- Primary retromolar malignant melanoma in a Latin American patient.The Journal of international medical research · 2020Article
- Analysis of Judicial Precedents Cases Regarding Skin Cancer from 1997 to 2017 in Republic of Korea.Annals of dermatology · 2019Article
- Small bowel obstruction due to intraluminal metastasis from malignant melanoma.Journal of surgical case reports · 2019Article
- Contemporary Treatment Approaches to Sinonasal Mucosal Melanoma.Current oncology reports · 2018Review
- Association of Surgical Approach and Margin Status With Oncologic Outcomes Following Gross Total Resection for Sinonasal Melanoma.JAMA otolaryngology-- head & neck surgery · 2017Article
- Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma.Oncotarget · 2017Article
- Clinics, prognosis and new therapeutic options in patients with mucosal melanoma: A retrospective analysis of 75 patients.Medicine · 2017Article
- Retrospective multicenter evaluation of patients diagnosed with mucosal melanoma: a study of Anatolian Society of Medical Oncology.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Prognosis of Mucosal, Uveal, Acral, Nonacral Cutaneous, and Unknown Primary Melanoma From the Time of First Metastasis.The oncologist · 2016Article
- Metastatic patterns and metastatic sites in mucosal melanoma: a retrospective study.European radiology · 2016Article
- Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition).Annals of translational medicine · 2015Review
- A Case of Amelanotic Malignant Melanoma of the Maxillary Sinus Presented with Intraoral Extension.The Malaysian journal of medical sciences : MJMS · 2015Article
- Primary localization and tumor thickness as prognostic factors of survival in patients with mucosal melanoma.PloS one · 2014Article
- Prevalence of malignant melanoma in anatomical sites of the oral cavity: A meta-analysis.Journal of oral and maxillofacial pathology : JOMFPReview
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection.
methodsOf the 141 patients who were diagnosed of non-cutaneous melanoma at 4 institutions in Korea between June 1992 and May 2005, 129 (91.5%) satisfied the selection criteria.
resultsOf the 129 noncutaneous melanoma patients, 14 patients had ocular melanoma and 115 patients had mucosal melanoma. For mucosal melanoma, anorectum was the most common anatomic site (n=39, 30.2%) which was followed by nasal cavity (n=30, 23.3%), genitourinary (n=21, 16.3%), oral cavity (n=14, 10.9%), upper gastrointestinal tract (n=6, 4.7%) and maxillary sinus (n=5, 3.9%) in the order of frequency. With the median 64.5 (range 4.3-213.0) months follow-up, the median overall survival were 24.4 months (95% CI 13.2-35.5) for all patients, and 34.6 (95% CI 24.5-44.7) months for curatively resected mucosal melanoma patients. Adverse prognostic factors of survival for 87 curatively resected mucosal melanoma patients were complete resection (R1 resection margin), and age>50 years. For 14 ocular melanoma, Survival outcome was much better than mucosal melanoma with 73.3% of 2 year OS and 51.2 months of median OS (P=.04).
conclusionPrognosis differed according to primary sites of noncutaneous melanoma. Based on our study, noncutaneous melanoma patients should be treated differently to improve survival outcome.
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