Evidence map›Paper›PMID 20425521›Full record

ReviewCurrent rheumatology reports2010

Drug-related myopathies of which the clinician should be aware.

Ritu Valiyil, Lisa Christopher-Stine

Open access · greenAbstract readReview
In one paragraph

Review in Current rheumatology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Rhabdomyolysis: a narrative review.Arquivos de neuro-psiquiatria · 2026
    Review
  4. Polymyxin B-Associated Muscle Injury: A Case Report.Infection and drug resistance · 2026
    Article
  5. Article
  6. Article
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  12. Is It Polymyositis?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  13. Observational
  14. Article
  15. Article
  16. A case of anti-HMGCR myopathy triggered by sodium/glucose co-transporter 2 (SGLT2) inhibitors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ritu ValiyilJohns Hopkins University School of Medicine, 5200 Eastern Avenue, MFL Center Tower, Suite 4100, Baltimore, MD 21224, USA.
Lisa Christopher-Stine
Johns Hopkins University · US

Funding

Idiopathic Inflammatory Myopathies: Improving Diagnosis and Predicting OutcomesK23AR053197 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CHRISTOPHER-STINE, LISA · 2006 to 2010
$682k
NIAMS NIH HHS K23 AR053197NIAMS NIH HHS K23-AR-053197
6 · The paper itself

Abstract

Many drugs used for therapeutic interventions can cause unanticipated toxicity in muscle tissue, often leading to considerable morbidity. A drug-induced, or toxic, myopathy is defined as the acute or subacute manifestation of myopathic symptoms such as muscle weakness, myalgia, creatine kinase elevation, or myoglobinuria that can occur in patients without muscle disease when they are exposed to certain drugs. A brief review of agents with a known association with myotoxicity and the proposed mechanisms linked to that toxicity is outlined; however, the purpose of this review is to highlight recent discoveries and advances in the field of toxic myopathies that have practical implications for practicing physicians. Because many drug-related myopathies are potentially reversible at early stages, it is important for clinicians to recognize toxic myopathies early in their course to determine when to discontinue therapy and potentially prevent irreversible muscle damage.

Indexed as

Drug-Related Side Effects and Adverse ReactionsHumansMuscle, SkeletalMuscular DiseasesRecovery of Function

Identifiers

PMID20425521
PMCPMC3092639
OpenAlexW2024718054

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.