Evidence map›Paper›PMID 20425517›Full record

ReviewCurrent rheumatology reports2010

Bone changes and fracture risk in individuals infected with HIV.

Amy H Warriner, Michael J Mugavero

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Bone and Infections: An Osteoimmunological Interplay.International journal of molecular sciences · 2026
    Review
  2. Is human immunodeficiency virus a risk factor for the development of nonunion?-a case-control study.OTA international : the open access journal of orthopaedic trauma · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Regional variability in changes in the incidence of hip fracture in the Spanish population (2000-2012).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Observational
  7. Review
  8. Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amy H WarrinerDivision of Endocrinology, Metabolism, and Diabetes, University of Alabama at Birmingham, FOT 702, 2000 6th Avenue South, Birmingham, AL 35233-0271, USA. warriner@uab.edu
Michael J Mugavero

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The life expectancy of individuals infected with HIV has improved greatly since the institution of combination antiretroviral therapy. However, many metabolic derangements have been discovered with long-term combination antiretroviral treatment, including lipodystrophy; insulin resistance; and, more recently, abnormal bone metabolism. It is well-documented that bone mineral density (BMD) in HIV-positive patients is lower compared with the expected BMD in non-HIV-positive patients. The underlying cause of lower BMD is unknown but is thought to be a multifactorial process. Conflicting evidence exists regarding the effect of antiretroviral exposure and duration of treatment, antiretroviral type, and cumulative HIV viral exposure on bone health. Here we review the bone changes that occur with HIV infection and treatment.

Indexed as

Antiretroviral Therapy, Highly ActiveBone DensityBone Density Conservation AgentsFemaleFractures, SpontaneousHIV InfectionsHumansMaleOsteoporosisRandomized Controlled Trials as TopicRisk FactorsBone Density Conservation Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.