Evidence map›Paper›PMID 20425506›Full record

ReviewCurrent allergy and asthma reports2010

Global airway disease beyond allergy.

Peter W Hellings, Emmanuel P Prokopakis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. A EUFOREA comment on a lost comorbidity of asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  5. Article
  6. Review
  7. Paranasal sinusitis at the initiation of chemotherapy is a risk factor for invasive fungal disease in children and adolescents with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  8. Recorded prevalence of nasal polyps increases with age.Postepy dermatologii i alergologii · 2021
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Local Allergic Rhinitis Revisited.Current allergy and asthma reports · 2020
    Review
  14. Contemporary Use of Corticosteroids in Rhinology.Current allergy and asthma reports · 2017
    Review
  15. Pediatric Severe Chronic Upper Airway Disease (P-SCUAD).Current allergy and asthma reports · 2015
    Review
  16. Observational
  17. Article
  18. Article
  19. A survey of clinical features of allergic rhinitis in adults.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
  20. Allergy as an epithelial barrier disease.Clinical and translational allergy · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Peter W HellingsDepartment of Otorhinolaryngology, Head, and Neck Surgery, University Hospitals Leuven, Kapucijnenvoer 33, Leuven, 3000, Belgium. peter.hellings@uzleuven.be
Emmanuel P Prokopakis
KU Leuven · BEUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides the anatomic continuity of the upper and lower airways, inflammation in one part of the airway influences the homeostasis of the other. The mechanisms underlying this interaction have been studied primarily in allergic disease, showing systemic immune activation, induction of inflammation at a distance, and a negative impact of nasal inflammation on bronchial homeostasis. In addition to allergy, other inflammatory conditions of the upper airways are associated with lower airway disease. Rhinosinusitis is frequently associated with asthma and chronic obstructive pulmonary disease. The impairment of purification, humidification, and warming up of the inspired air by the nose in rhinosinusitis may be responsible in part for bronchial pathology. The resolution of sinonasal inflammation via medical and/or surgical treatment is responsible for the beneficial effect of the treatment on bronchial disease. This article provides a comprehensive overview of the current knowledge of upper and lower airway communication beyond allergic disease.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveRhinitisSinusitisBronchiHumansNose

Identifiers

PMID20425506
OpenAlexW2019941977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.