Evidence map›Paper›PMID 20425483›Full record

ReviewCurrent gastroenterology reports2010

Cryptogenic cirrhosis: what are we missing?

Stephen Caldwell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 52 citations in OpenAlex.

  1. Genetic testing in liver diseases: Clinical applications.JHEP reports : innovation in hepatology · 2026
    Review
  2. [Proportion and clinical characteristics of probable metabolic-associated fatty liver disease-related cirrhosis in cryptogenic cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  3. Article
  4. Article
  5. Cellular Mechanisms of Liver Fibrosis.Frontiers in pharmacology · 2021
    Review
  6. Observational
  7. Article
  8. Article
  9. Age and ethnicity in cirrhosis.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2014
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. An Endocrine Perspective of Nonalcoholic Fatty Liver Disease (NAFLD).Therapeutic advances in endocrinology and metabolism · 2011
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen CaldwellDigestive Health Center, GI/Hepatology Division, University of Virginia Health Science Center, Charlottesville, VA 22908-0708, USA. shc5c@virginia.edu
University of Virginia Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptogenic cirrhosis remains a common clinical condition although recent advances have allowed for a better understanding of underlying conditions and associations. The evolving terminology applied to this condition has resulted in some confusion and persistent variation among pathologists and clinicians. Typical patients are middle aged with only minor liver enzyme abnormalities. Presentations range from incidentally discovered cirrhosis to complications of advanced portal hypertension and hepatocellular cancer. Clinicopathologic analysis of these patients indicates that the leading causes include previously unrecognized nonalcoholic steatohepatitis, silent autoimmune hepatitis, non-B, non-C viral hepatitis, and occult past ethanol exposure. In this article, we review these associations as well as a proposed classification system for cryptogenic cirrhosis and other lesser known genetic and syndromic associations that warrant consideration when evaluating these individuals.

Indexed as

Fatty LiverLiver CirrhosisBiomarkersHepatitis, AutoimmuneHepatitis, Viral, HumanHumansLiver Diseases, AlcoholicLiver Function TestsLiver TransplantationTerminology as TopicBiomarkers

Identifiers

PMID20425483
OpenAlexW1984650281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.