Evidence map›Paper›PMID 20425184›Full record

ReviewCurrent cardiology reports2010

In vivo imaging and monitoring of transplanted stem cells: clinical applications.

Martin Rodriguez-Porcel

Abstract readReview
In one paragraph

Review in Current cardiology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. OPTRACE: Optical Imaging-Guided Transplantation and Tracking of Cells in the Mouse Brain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Detection limit ofEJNMMI research · 2020
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Clinical Hepatocyte Transplantation: What Is Next?Current transplantation reports · 2017
    Article
  12. Article
  13. Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2016
    Article
  14. Article
  15. Review
  16. Advances in Molecular Imaging Strategies forBioMed research international · 2016
    Review
  17. Review
  18. Article
  19. Article
  20. Magnetic resonance imaging of transplanted stem cell fate in stroke.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Martin Rodriguez-PorcelStabile 4-56, Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Rodriguez.m@mayo.edu

Funding

Role of Oxidative Stress in Stem Cell Differentiation and SurvivalR00HL088048 · NHLBI · MAYO CLINIC ROCHESTER · PI RODRIGUEZ-PORCEL, MARTIN · 2009 to 2011
$747k
Role of Oxidative Stress in Stem Cell Differentiation and SurvivalK99HL088048 · NHLBI · MAYO CLINIC ROCHESTER · PI RODRIGUEZ-PORCEL, MARTIN · 2007 to 2008
$175k
NHLBI NIH HHS HL88048NHLBI NIH HHS K99 HL088048NHLBI NIH HHS R00 HL088048
6 · The paper itself

Abstract

Regenerative medicine using stem cells has appeared as a potential therapeutic alternative for coronary artery disease, and stem cell clinical studies are currently on their way. However, initial results of these studies have provided mixed information, in part because of the inability to correlate organ functional information with the presence/absence of transplanted stem cells. Recent advances in molecular biology and imaging have allowed the successful noninvasive monitoring of transplanted stem cells in the living subject. In this article, different imaging strategies (direct labeling, indirect labeling with reporter genes) to study the viability and biology of stem cells are discussed. In addition, the limitations of each approach and imaging modality (eg, single photon emission computed tomography, positron emission tomography, and MRI) and their requirements for clinical use are addressed. Use of these strategies will be critical as the different regenerative therapies are being tested for clinical use.

Indexed as

Molecular ImagingStem Cell TransplantationCoronary Artery DiseaseGenes, ReporterLuminescent MeasurementsMagnetic Resonance ImagingPositron-Emission TomographyTomography, Emission-Computed, Single-Photon

Identifiers

PMID20425184
PMCPMC2861794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.