ArticleJournal of assisted reproduction and genetics2010
Male infertility in China: laboratory finding for AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China.
Article in Journal of assisted reproduction and genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Correlation between reproductive hormone levels and genetic abnormalities in patients with non-obstructive azoospermia and oligospermia.Translational andrology and urology · 2026Article
- Clinical Analysis of Y Chromosome Microdeletions and Chromosomal Aberrations in 1596 Male Infertility Patients of the Zhuang Ethnic Group in Guangxi.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Detection of AZF microdeletions and analysis of reproductive hormonal profiles in Hainan men undergoing assisted reproductive technology.BMC urology · 2024Article
- RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.Cell & bioscience · 2023Article
- Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India.Molecular genetics & genomic medicine · 2021Article
- External and Genetic Conditions Determining Male Infertility.International journal of molecular sciences · 2020Review
- Chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia in Eastern China.The Journal of international medical research · 2020Article
- Some of the Factors Involved in Male Infertility: A Prospective Review.International journal of general medicine · 2020Review
- Incidence of Y chromosome microdeletions in patients with Klinefelter syndrome.Journal of endocrinological investigation · 2019Article
- Multicenter study of genetic abnormalities associated with severe oligospermia and non-obstructive azoospermia.The Journal of international medical research · 2018Article
- High prevalence of genetic abnormalities in Middle Eastern patients with idiopathic non-obstructive azoospermia.Journal of assisted reproduction and genetics · 2013Article
- Chromosomal abnormalities in patients with oligozoospermia and non-obstructive azoospermia.Journal of assisted reproduction and genetics · 2013Article
- Cytogenetic abnormalities and Y-chromosome microdeletions in infertile Syrian males.Biomedical reports · 2013Article
- Impact of chromosomal heteromorphisms on reproductive failure and analysis of 38 heteromorphic pedigrees in Northeast China.Journal of assisted reproduction and genetics · 2013Article
- Clinical data for 185 infertile Iranian men with Y-chromosome microdeletion.Journal of assisted reproduction and genetics · 2012Article
- Genetic screening for chromosomal abnormalities and Y chromosome microdeletions in Chinese infertile men.Journal of assisted reproduction and genetics · 2012Article
- Male infertility in Northeast China: a cytogenetic study of 135 patients with non-obstructive azoospermia and severe oligozoospermia.Journal of assisted reproduction and genetics · 2012Article
- Azoospermia related to a unique karyotype: 45,XY,-13,-19,+der(19)t(13;19)(q12;p13).Journal of applied genetics · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposesTo investigate the frequencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. Moreover, to compare the prevalence of these abnormalities with other countries and regions in the world.
methods305 infertile men were enrolled. A complete semen analysis and reproductive hormones were measured according to standard methods. Multiplex polymerase chain reaction (PCR) amplification using nine specific sequence-tagged sites (STS) were used to detect AZF microdeletions. Karyotype analyses were performed on peripheral blood lymphocytes with standard G-banding.
resultsOf the 305 infertile men, 28 (9.2%) had AZF microdeletions and 26 (8.5%) had chromosomal abnormalities. The most frequent microdeletions were in the AZFc+d, followed by AZFc, AZFb+c+d and AZFa. A total of 19 patients (82.6%) had Klinefelter's syndrome (47, XXY) in the azoospermic group.
conclusionsThe freqencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China were comparable with infertile men from other countries and regions. However, there was a slightly higher prevalence rate of AZF microdeletions in oligozoospermic patients than reported in previous studies.
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