ReviewCurrent neurology and neuroscience reports2010
The genetics of pediatric brain tumors.
Review in Current neurology and neuroscience reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Review
- A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).Pediatric blood & cancer · 2021Article
- Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury.Cerebellum (London, England) · 2018Article
- Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.Cellular and molecular neurobiology · 2018Review
- Integrated mRNAseq and microRNAseq data analysis for grade III gliomas.Molecular medicine reports · 2017Article
- Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival.Journal of neuro-oncology · 2017Article
- Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity.BMC pharmacology & toxicology · 2017Article
- Understanding Ependymoma Oncogenesis: an Update on Recent Molecular Advances and Current Perspectives.Molecular neurobiology · 2017Review
- Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility.Oncotarget · 2016Article
- Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016Article
- Posterior fossa ependymoma: current insights.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Review
- Pediatric brain tumor cell lines.Journal of cellular biochemistry · 2015Article
- Anti-miR21 oligonucleotide enhances chemosensitivity of T98G cell line to doxorubicin by inducing apoptosis.American journal of cancer research · 2015Article
- Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors.Cancer genetics · 2014Article
- Cytogenetic prognostication within medulloblastoma subgroups.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Article
- TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.Acta neuropathologica · 2013Article
- Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma.Gene therapy · 2013Article
- Medulloblastoma biology in the post-genomic era.Future oncology (London, England) · 2012Review
- Molecular subgroups of medulloblastoma.Expert review of neurotherapeutics · 2012Review
- Long-term epilepsy-associated tumors.Brain pathology (Zurich, Switzerland) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain tumors are the most common childhood solid malignancy and the leading cause of cancer-related death in children. Medulloblastoma, ependymoma, supratentorial primitive neuroectodermal tumors, and pilocytic astrocytoma are the most prevalent types, all of which are clinically, histologically, and genetically heterogeneous. Despite an incomplete molecular understanding of these tumors, we have made significant headway in the past 5 years in identifying and classifying important genetic alterations and pathways central to the disease process. This review summarizes our current state of knowledge, emphasizes recent seminal findings in the field, and proposes future research efforts needed to further characterize the genetic basis of pediatric brain tumors.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.