Evidence map›Paper›PMID 20424399›Full record

Trial reportThe Physician and sportsmedicine2010

Is exercise adherence associated with clinical outcomes in patients with advanced heart failure?

Lorraine S Evangelista, Michele A Hamilton, Gregg C Fonarow, Kathleen Dracup

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Physician and sportsmedicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Home-based versus centre-based cardiac rehabilitation.The Cochrane database of systematic reviews · 2017
    Pooled it
  4. Exercise-based rehabilitation for heart failure.The Cochrane database of systematic reviews · 2014
    Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Psychological responses and adherence to exercise in heart failure.Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses
    Trial
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Using wearable technology to predict health outcomes: a literature review.Journal of the American Medical Informatics Association : JAMIA · 2018
    Review
  20. The relationship between exercise dose and health-related quality of life with a phase III cardiac rehabilitation program.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lorraine S EvangelistaUniversity of California Los Angeles, School of Nursing, Los Angeles, CA 90095-6918, USA. levangel@ucla.edu
Michele A Hamilton
Gregg C Fonarow
Kathleen Dracup
UCLA Medical Center · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CATHERINE A SARKISIAN · 2002 to 2026
$19.7M
Examining the Effects of High Protein Diet on Outcomes in Heart Failure PatientsR01HL093466 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EVANGELISTA, LORRAINE S · 2009 to 2013
$1.9M
NHLBI NIH HHS 1R01HL093466-01NHLBI NIH HHS R01 HL093466NIA NIH HHS P30 AG021684NIA NIH HHS P30-AG02-1684
6 · The paper itself

Abstract

backgroundThere is limited research to support the effect of exercise adherence on clinical outcomes in patients with heart failure (HF). This secondary analysis was conducted on the intervention arm of an exercise training study in patients with HF to assess whether adherence and the dose of treatment exposure were associated with clinical outcomes, functional performance (maximum oxygen consumption [VO2], anaerobic threshold, and workload), and quality of life (QOL).

methodsSeventy-one patients (average age, 54 +/- 12.5 years; male, 66%; Caucasian, 66%; married, 61%; New York Heart Association class II-III, 97.2%; and average ejection fraction, 26.4% +/- 6.5%) were included in the current study. Patients with an increase >/= 18% in the amount of exercise from baseline to 6 months, as measured by pedometers, were categorized as adherers (n = 38); patients who had no change or an increase in the amount of exercise of <18% were categorized as nonadherers (n = 33).

resultsThe 2 groups were significantly different in the composite endpoint of all-cause hospitalization, emergency room admissions, and death/urgent transplantation (hazard ratio, 0.31; 95% confidence interval, 0.159-0.635; P < 0.001). Adherers had greater improvements in functional performance and QOL compared with nonadherers (P< 0.001).

conclusionThese findings suggest that among patients with advanced HF, adherence to exercise is associated with more favorable clinical outcomes. There is also a positive dose-response relationship between the amount of exercise performed and improvement in functional performance and QOL.

Indexed as

Anaerobic ThresholdExercise TherapyPatient ComplianceQuality of LifeAdultAgedFemaleHeart FailureHumansKaplan-Meier EstimateMaleMiddle Aged

Identifiers

PMID20424399
PMCPMC2909849
OpenAlexW2093588033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.