Evidence map›Paper›PMID 20422638›Full record

ArticleProteomics2010

The secreted proteome profile of developing Dictyostelium discoideum cells.

Deenadayalan Bakthavatsalam, Richard H Gomer

Abstract read
In one paragraph

Article in Proteomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. The Proteome ofProteomes · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Proteomic Analysis of Dictyostelium discoideum by Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  6. Article
  7. Cells · 2022
    Review
  8. Altered protein secretion in Batten disease.Disease models & mechanisms · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Calmodulin-mediated events during the life cycle of the amoebozoan Dictyostelium discoideum.Biological reviews of the Cambridge Philosophical Society · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Deenadayalan BakthavatsalamDepartment of Biochemistry and Cell Biology, Rice University, Houston, TX, USA.
Richard H Gomer

Funding

An autocrine repressor of cell proliferationR01GM074990 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI GOMER, RICHARD H · 2006 to 2009
$1.1M
NIGMS NIH HHS R01 GM074990
6 · The paper itself

Abstract

Dictyostelium discoideum is a unicellular eukaryote that, when starved, aggregates to form multicellular structures. In this report, we identified the proteins secreted by developing Dictyostelium cells using MS-based proteomics. A total of 349 different secreted proteins were identified, indicating that at least 2.6% of the 13 600 predicted proteins in the Dictyostelium genome are secreted. Gene ontology analysis suggests that many of the secreted proteins are involved in protein and carbohydrate metabolism, and proteolysis.

Indexed as

DictyosteliumProteomeProteomicsProtozoan ProteinsProteomeProtozoan Proteins

Identifiers

PMID20422638
PMCPMC2926150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.