ArticleVirchows Archiv : an international journal of pathology2010
High-resolution genome-wide analysis of chromosomal alterations in elastofibroma.
Article in Virchows Archiv : an international journal of pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Rare rectal elastofibroma: diagnostic challenges and case report.Discover oncology · 2025Article
- A Case of an Oral Elastofibromatous Lesion: A Clinicopathological Analysis With a Literature Review.Case reports in dentistry · 2025Article
- A 78-Year-Old Man with Elastofibroma Dorsi Presenting as a Left Subscapular Mass.The American journal of case reports · 2024Article
- Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory.Biomolecules · 2022Article
- Surgery for elastofibroma dorsi: optimizing the management of a benign tumor-an analysis of 70 cases.Journal of thoracic disease · 2020Article
- Retrospective analysis of 73 cases of elastofibroma.Annals of the Royal College of Surgeons of England · 2020Article
- Elastofibroma of the gluteal region with a concomitant contralateral lesion: case report and review of the literature.Skeletal radiology · 2017Review
- Elastofibroma dorsi: Clinical evaluation of 61 cases and review of the literature.Acta orthopaedica et traumatologica turcica · 2017Article
- Upregulation of TGF-β1 and basic FGF in elastofibroma: an immunohistochemical analysis.Medical molecular morphology · 2016Article
- Elastofibroma dorsi: a histochemical and immunohistochemical study.European journal of histochemistry : EJH · 2015Article
- Elastofibroma: clinical results after resection of a rare tumor entity.Orthopedic reviews · 2014Article
- Elastofibromatous change of the intestine: report of four lesions from three patients with review of the literature.International journal of clinical and experimental pathology · 2014Review
- Painful elastofibroma dorsi: a report of a case and a brief review of the literature.Case reports in orthopedics · 2013Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elastofibroma is a rare, benign fibrous proliferation that most commonly occur in periscapular soft tissues and is characterized by accumulated elastic fibers. Although the lesion is generally regarded as a reactive process, an unusual fibroblastic pseudotumor or as a fibroelastic tumor-like lesion, its etiology remains unknown. Cytogenetic studies in these lesions detected chromosomal instability and some recurrent clonal chromosomal changes, which raised the possibility that the lesion represents a neoplastic process. Here, we report the genomic alterations detected by array-based comparative genomic hybridization (aCGH) and by multiplex ligation-dependent probe amplification (MLPA) in two cases of elastofibroma. Both cases showed losses on 1p, 13q, 19p, and 22q by aCGH. In addition, deletion of CASR (3q21), GSTP1 (11q13), BRCA2 (13q12) and gains on APC (5q21) and PAH (12q23) were observed by MLPA in both samples. Genomic screening studies of this fibrous proliferation may lead to identify chromosomal regions containing genes involved in the development of elastofibromas.
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