ReviewPlant signaling & behavior2010
RNA-directed DNA methylation: mechanisms and functions.
Review in Plant signaling & behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Genome-Wide DNA Methylation Analysis of Performance Variation in the 5000-m Speed Race of Yili Horses.Animals : an open access journal from MDPI · 2026Article
- Genome-wide analysis of strand-specific transcription and DNA methylation inFrontiers in microbiology · 2026Article
- Ergodic Manipulation of Genome Chaos: Innovative Strategies against Malignant Progression.Current cancer drug targets · 2025Review
- DNA methylation orchestrates secondary metabolite biosynthesis and transport in Papaver somniferum.PloS one · 2025Article
- Emerging Roles of Epigenetics in Grapevine and Winegrowing.Plants (Basel, Switzerland) · 2024Review
- Natural epialleles of Arabidopsis SUPERMAN display superwoman phenotypes.Communications biology · 2020Article
- Exogenous Promoter Triggers APETALA3 Silencing through RNA-Directed DNA Methylation Pathway inInternational journal of molecular sciences · 2019Article
- An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs).Frontiers in bioengineering and biotechnology · 2019Article
- Context-Dependent Developmental Effects of Parental Shade Versus Sun Are Mediated by DNA Methylation.Frontiers in plant science · 2018Article
- The Importance of ncRNAs as Epigenetic Mechanisms in Phenotypic Variation and Organic Evolution.Frontiers in microbiology · 2017Review
- Genome editing: the road of CRISPR/Cas9 from bench to clinic.Experimental & molecular medicine · 2016Review
- Seasonal-based temporal changes fluctuate expression patterns of TXS, DBAT, BAPT and DBTNBT genes alongside production of associated taxanes in Taxus baccata.Plant cell reports · 2016Article
- Transgenerational plasticity is sex-dependent and persistent in yellow monkeyflower (Environmental epigenetics · 2016Article
- Activities and specificities of homodimeric TALENs in Saccharomyces cerevisiae.Current genetics · 2014Article
- Epigenomics and allergic disease.Epigenomics · 2013Review
- The role of methylation of DNA in environmental adaptation.Integrative and comparative biology · 2013Article
- Poplars with a PtDDM1-RNAi transgene have reduced DNA methylation and show aberrant post-dormancy morphology.Planta · 2013Article
- Article
- Snf2 family gene distribution in higher plant genomes reveals DRD1 expansion and diversification in the tomato genome.PloS one · 2013Article
- Inter-species grafting caused extensive and heritable alterations of DNA methylation in Solanaceae plants.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epigenetic RNA based gene silencing mechanisms play a major role in genome stability and control of gene expression. Transcriptional gene silencing via RNA-directed DNA methylation (RdDM) guides the epigenetic regulation of the genome in response to disease states, growth, developmental and stress signals. RdDM machinery is composed of proteins that produce and modify 24-nt- long siRNAs, recruit the RdDM complex to genomic targets, methylate DNA and remodel chromatin. The final DNA methylation pattern is determined by either DNA methyltransferase alone or by the combined action of DNA methyltransferases and demethylases. The dynamic interaction between RdDM and demethylases may render the plant epigenome plastic to growth, developmental, and environmental cues. The epigenome plasticity may allow the plant genome to assume many epigenomes and to have the right epigenome at the right time in response to intracellular or extracellular stimuli. This review discusses recent advances in RdDM research and considers future perspectives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.