ReviewJournal of clinical microbiology2010
Use of plasma procalcitonin levels as an adjunct to clinical microbiology.
Review in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Persistently High Procalcitonin and C-Reactive Protein Are Good Predictors of Infection in Acute Necrotizing Pancreatitis: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2024Pooled it
- Serum Procalcitonin to Support Early Triage for Possible Systemic Infection in Patients with Endophthalmitis.Diagnostics (Basel, Switzerland) · 2026Article
- Serum Procalcitonin in Culture-Confirmed Melioidosis: A Systematic Review and Meta-Analysis with Narrative Evaluation of Clinical and Prognostic Implications.Diseases (Basel, Switzerland) · 2026Review
- Procalcitonin for Predicting Sepsis in Infants in the Emergency Department: A Retrospective Study.Pediatric health, medicine and therapeutics · 2026Article
- Longitudinal Analysis of Traditional Inflammatory Markers (IL-6, CRP) Juxtaposed With Heparin-Binding Protein (HBP) and Serum Amyloid A Protein Component (SAA) During Acute Infection and Convalescence From COVID-19 Infection in the Context of Initial Viral Load and Markers of Tissue Destruction.Journal of immunology research · 2025Article
- Article
- A Retrospective Study: Evaluating the Impact of the COVID-19 Pandemic on Inflammatory Markers in Hospitalized Patients.Infectious disease reports · 2024Article
- Procalcitonin and qSOFA as a Marker of Mortality in Sepsis.Reviews on recent clinical trials · 2024Observational
- Procalcitonin in the Post-Operative Burn Patient.European burn journal · 2023Article
- Misleading Procalcitonin in Patients With Staphylococcus aureus Bacteremia: A Report of Two Cases.Cureus · 2023Article
- Detecting Diabetic Ketoacidosis with Infection: Combating a Life-Threatening Emergency with Practical Diagnostic Tools.Diagnostics (Basel, Switzerland) · 2023Review
- Integrated Bioluminescent Immunoassays for High-Throughput Sampling and Continuous Monitoring of Cytokines.Analytical chemistry · 2023Article
- Procalcitonin for antimicrobial stewardship among cancer patients admitted with COVID-19.eLife · 2022Article
- Use of Host Response to Refine the Diagnosis of Group A Streptococcal Pharyngitis.Journal of the Pediatric Infectious Diseases Society · 2022Article
- Article
- Procalcitonin as a Potential Biomarker in the Study of Babesiosis Caused byPathogens (Basel, Switzerland) · 2022Article
- Ventilator-associated pneumonia in critically ill patients with COVID-19 infection: a narrative review.ERJ open research · 2022Review
- Bio-Functionalized Magnetic Nanoparticles for the Immunoassay of C-Reactive Protein and Procalcitonin in Cervicovaginal Secretions of Pregnant Women with Preterm Prelabor Rupture of Membranes to Predict Early-Onset Neonatal Sepsis.International journal of nanomedicine · 2022Article
- Clinical value of procalcitonin in critically ill patients infected by SARS-CoV-2.The American journal of emergency medicine · 2021Observational
- Procalcitonin predicts the severity of cystic fibrosis pulmonary exacerbations and readmissions in adult patients: a prospective cohort study.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Procalcitonin (PCT) is synthesized by a large number of tissues and organs in response to invasion by pathogenic bacteria, fungi, and some parasites. Current PCT assays are rapid, specific, and of sufficient sensitivity to detect increases in PCT serum levels within 4 to 6 h of initiation of infection. Clinically, PCT levels may help in decisions regarding the need for empirical antibiotic therapy, "source control" of infection, and duration of antibiotic therapy. The addition of PCT levels to bacterial culture and viral detection results can assist with the separation of colonization and invasion by pathogenic bacteria.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.