ReviewAnnual review of nutrition2010
Iron homeostasis and the inflammatory response.
Review in Annual review of nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
226 citing papers in PubMed, 1 synthesis or guideline pooled it, 474 citations in OpenAlex.
- The role of genetically predicted serum iron levels on neurodegenerative and cardiovascular traits.Scientific reports · 2024Pooled it
- Impact of an eight-week isocaloric vegan dietary intervention on hemogram parameters and lymphocyte subsets: a randomized-controlled trial.BMC medicine · 2026Trial
- Medium cut-off dialyzer improves erythropoiesis stimulating agent resistance in a hepcidin-independent manner in maintenance hemodialysis patients: results from a randomized controlled trial.Scientific reports · 2020Trial
- Trial
- Efficacy of Lactoferrin Oral Administration in the Treatment of Anemia and Anemia of Inflammation in Pregnant and Non-pregnant Women: An Interventional Study.Frontiers in immunology · 2018Trial
- Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection - a double blind, randomised controlled trial in Burkina Faso.BMC medicine · 2017Trial
- Effects of Traditional Chinese Herbal Extracts on Tear Staining, Iron Status, Immune Function, and Antioxidant Capacity in Dogs.Animals : an open access journal from MDPI · 2026Article
- Reexamining the Role of Amyloid β Clearance from the Brain: Exporting Labile Iron from the Interstitial Fluid Performs a Protective Function.International journal of molecular sciences · 2026Review
- Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson's and inflammatory bowel disease.NPJ Parkinson's disease · 2026Article
- Transcriptional changes related to metabolic and iron acquisition strategies of avian pathogenicFrontiers in cellular and infection microbiology · 2026Article
- The Time Course of Serum Iron and Serum Ferritin Concentrations Post-COVID-19 and Influenza Vaccinations.Case reports in infectious diseases · 2026Article
- A DGA-aligned pulse-protein diet may support iron homeostasis in older adults: an exploratory analysis of the PRODMED1 trial.Frontiers in nutrition · 2026Article
- Obesity, diet, and inflammation in Filipino schoolchildren: an opinion paper.Frontiers in nutrition · 2026Article
- Iron as a Modifiable Factor for Adverse Pregnancy Outcomes: Refining and Understanding Causal Estimates Using Mendelian Randomization.Biological trace element research · 2025Article
- Dietary Patterns Among Patients With Beta-Thalassemia Major in Vietnam.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Maternal systemic iron homeostasis in diabetes-in-pregnancy: A cross-sectional analytical study from a tertiary health care centre of South India.Saudi medical journal · 2025Article
- Accelerated increase in ferritin levels during menopausal transition as a marker of metabolic health.Scientific reports · 2025Article
- Serum ferritin levels linked to cognitive decline and biomarker profiles in dementia with lewy bodies.Acta neurologica Belgica · 2025Article
- Impact of inflammatory status on intestinal iron absorption in older hospitalized patients.European journal of clinical nutrition · 2025Article
- Upregulation of the Antioxidant Response-Related microRNAs miR-146a-5p and miR-21-5p in Gestational Diabetes: An Analysis of Matched Samples of Extracellular Vesicles and PBMCs.International journal of molecular sciences · 2025Article
166 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Iron and its homeostasis are intimately tied to the inflammatory response. The adaptation to iron deficiency, which confers resistance to infection and improves the inflammatory condition, underlies what is probably the most obvious link: the anemia of inflammation or chronic disease. A large number of stimulatory inputs must be integrated to tightly control iron homeostasis during the inflammatory response. In order to understand the pathways of iron trafficking and how they are regulated, this article presents a brief overview of iron homeostasis. A major focus is on the regulation of the peptide hormone hepcidin during the inflammatory response and how its function contributes to the process of iron withdrawal. The review also summarizes new and emerging information about other iron metabolic regulators and effectors that contribute to the inflammatory response. Potential benefits of treatment to ameliorate the hypoferremic condition promoted by inflammation are also considered.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.