ArticleWorld journal of gastroenterology2010
MRI-determined fat content of human liver, pancreas and kidney.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 99 citations in OpenAlex.
- Changes in Kidney Fat upon Dietary-Induced Weight Loss.Nutrients · 2022Trial
- Development and reproducibility of a computed tomography-based measurement of renal sinus fat.BMC nephrology · 2011Trial
- MRI measurements of pancreatic fat content in the general population and their relationship with age, gender, and body mass index.Medicine · 2026Article
- From NAFPD to MAFPD: a literature review of implications of a nomenclature change.Hepatobiliary surgery and nutrition · 2025Review
- Challenges in studying microplastics in human brain.Nature medicine · 2025Article
- Renal Fat Accumulation Assessed by MRI or CT and Its Association with Clinical and Metabolic Disorders: A Systematic Imaging Review.Journal of clinical medicine · 2025Review
- Quantifying renal lipid accumulation in obese murine models using Magnetic Resonance Imaging (MRI).Biochemical and biophysical research communications · 2025Article
- The Impact of Exercise Training Plus Dietary Interventions on Ectopic Fat in Population with Overweight/Obesity with and without Chronic Disease: A Systematic Review, Meta-analysis, and Metaregression of Randomized Clinical Trials.Current developments in nutrition · 2025Review
- UsingFrontiers in physiology · 2025Article
- Correlation between Pancreatic Fat Deposition and Metabolic Syndrome: Relationships with Location in the Pancreas and Sex.Internal medicine (Tokyo, Japan) · 2024Article
- Intrapancreatic fat deposition is unrelated to liver steatosis in metabolic dysfunction-associated steatotic liver disease.JHEP reports : innovation in hepatology · 2024Article
- Pathophysiological Mechanisms and Clinical Associations of Non-Alcoholic Fatty Pancreas Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Pancreatic steatosis and metabolic pancreatic disease: a new entity?Internal and emergency medicine · 2023Review
- Effect of body mass index (BMI) on image contrast in the hepatobiliary phase of Gd-EOB-DTPA-enhanced-MRI and the feasibility of the application of half-dose Gd-EOB-DTPA to hepatobiliary phase imaging in patients with a BMI less than 24: a comparative study.Quantitative imaging in medicine and surgery · 2023Article
- Fatty infiltration of the pancreas: a systematic concept analysis.Frontiers in medicine · 2023Review
- New insights into the role of empagliflozin on diabetic renal tubular lipid accumulation.Diabetology & metabolic syndrome · 2022Article
- In Vivo Renal Lipid Quantification by Accelerated Magnetic Resonance Spectroscopic Imaging at 3T: Feasibility and Reliability Study.Metabolites · 2022Article
- Hyperechoic pancreas on ultrasonography: an analysis of its severity and clinical implications.Ultrasonography (Seoul, Korea) · 2022Article
- Nonalcoholic Fatty Pancreas Disease: Role in Metabolic Syndrome, "Prediabetes," Diabetes and Atherosclerosis.Digestive diseases and sciences · 2022Review
- Quantitative Analysis of Pancreatic Fat in Children with Obesity Using Magnetic Resonance Imaging and Ultrasonography.Pediatric gastroenterology, hepatology & nutrition · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight.
methodsMagnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon's two point technique were used in this study to quantify fat in liver, pancreas as well as kidney.
resultsIn 36 volunteers with body mass index (BMI) ranging from 20.0 to 42.9 kg/m(2), the median fat content of liver, pancreas and kidney was 2.3% (interquartile range: 0.2%-7.8%), 2.7% (1.0%-6.5%) and 0.7% (0.1%-1.4%), respectively. BMI and subcutaneous fat correlated significantly with liver and pancreas fat content. We show for the first time the significant correlation of liver and pancreas fat content in healthy controls (r = 0.43, P < 0.01). These observations are related to body weight as measured by BMI and the amount of subcutaneous fat. Kidney fat content is very low and correlates with none of the other fat depots.
conclusionRenal lipid accumulation, unlike the coupled accumulations of fat in liver and pancreas, is not observed in obese subjects. Unlike suggestions made in previous studies, renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.