ReviewWorld journal of gastroenterology2010
Effect of the timing of gluten introduction on the development of celiac disease.
Review in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Pooled it
- Seroprevalence of Anti-tTg-IgA among Symptomized Celiac Disease Patients and Their Correlation with Rotavirus Infection.BioMed research international · 2022Article
- The Role of Early Programming and Early Nutrition on the Development and Progression of Celiac Disease: A Review.Nutrients · 2020Review
- An updated overview of spectrum of gluten-related disorders: clinical and diagnostic aspects.BMC gastroenterology · 2020Review
- Pathogenesis of Celiac Disease and Other Gluten Related Disorders in Wheat and Strategies for Mitigating Them.Frontiers in nutrition · 2020Review
- Transglutaminase 2 and Transglutaminase 2 Autoantibodies in Celiac Disease: a Review.Clinical reviews in allergy & immunology · 2019Review
- Genetic and Environmental Contributors for Celiac Disease.Current allergy and asthma reports · 2019Review
- Potential risk factors for celiac disease in childhood: a case-control epidemiological survey.Clinical and experimental gastroenterology · 2019Article
- Celiac disease: From pathophysiology to treatment.World journal of gastrointestinal pathophysiology · 2017Review
- Early Infant Feeding Practices May Influence the Onset of Symptomatic Celiac Disease.Pediatric gastroenterology, hepatology & nutrition · 2016Article
- The Interaction among Microbiota, Immunity, and Genetic and Dietary Factors Is the Condicio Sine Qua Non Celiac Disease Can Develop.Journal of immunology research · 2015Review
- Involvement of heat shock proteins in gluten-sensitive enteropathy.World journal of gastroenterology · 2014Review
- Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology.Nutrients · 2013Review
- Immune development and intestinal microbiota in celiac disease.Clinical & developmental immunology · 2012Review
- Influence of environmental and genetic factors linked to celiac disease risk on infant gut colonization by Bacteroides species.Applied and environmental microbiology · 2011Article
- Novel trends in celiac disease.Cellular & molecular immunology · 2011Review
- Spectrum of Celiac disease in Paediatric population: Experience of Tertiary Care Center from Pakistan.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease (CD) is a permanent auto-immune enteropathy, triggered in genetically predisposed individuals by the ingestion of dietary gluten. Gluten is the alcohol-soluble protein component of the cereals wheat, rye and barley. CD is a multifactorial condition, originating from the interplay of genetic and environmental factors. The necessary environmental trigger is gluten, while the genetic predisposition has been identified in the major histocompatibility complex region on chromosome 6p21, with over 90% of CD patients expressing HLA DQ2 and the remaining celiac patients express DQ8. The fact that only about 4% of DQ2/8-positive individuals exposed to gluten develop CD, has led to the recognition that other genetic and environmental factors are also necessary. In the last few years, several epidemiological studies have suggested that the timing of the introduction of gluten, as well as the pattern of breastfeeding, may play an important role in the subsequent development of CD. Here, we present and review the most recent evidences regarding the effect of timing of gluten introduction during weaning, the amount of gluten introduced and simultaneous breastfeeding, on the development of CD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.