Evidence map›Paper›PMID 20419813›Full record

ArticleJournal of medical virology2010

Human herpesvirus 6-A, 6-B, and 7 in vitreous fluid samples.

Jeffrey I Cohen, Gary Fahle, Margaret A Kemp, Kathleen Apakupakul, Todd P Margolis

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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  7. High rates of cerebral toxoplasmosis in HIV patients presenting with meningitis in Accra, Ghana.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jeffrey I CohenMedical Virology Section, Laboratory of Clinical Infectious Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1888, USA. jcohen@niaid.nih.gov
Gary Fahle
Margaret A Kemp
Kathleen Apakupakul
Todd P Margolis
National Institutes of Health Clinical Center · USNational Institute of Allergy and Infectious Diseases · USSan Francisco Foundation · USUniversity of California, San Francisco · US

Funding

Pathogenesis and Chemotherapy of Human Virus InfectionsZIAAI000058 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI COHEN, JEFFREY · 2009 to 2025
$8.8M
THE PATHOGENESIS AND CHEMOTHERAPY OF HERPESVIRUS INFECTIONS IN MANZ01AI000058 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI COHEN, JEFFREY · 1985 to 2008
$680k
Intramural NIH HHS Z01 AI000058
6 · The paper itself

Abstract

Human herpesvirus 6 and 7 (HHV-6, HHV-7) have been associated with several neurologic syndromes and have been detected in nervous tissue from healthy persons; however, only two cases of HHV-6A have been reported to be associated with intraocular inflammatory disease. Vitreous fluid was tested from 101 patients, including 69 samples from patients with ocular inflammation including CMV retinitis, idiopathic retinitis, iritis, and vitritis, for HHV-6A, HHV-6B, and HHV-7 DNA by PCR. HHV-6A DNA (4,950 copies per ml) was detected in vitreous fluid from one patient with CMV retinitis, HHV-6B DNA (10,140 copies per ml) was detected in vitreous fluid from one patient with idiopathic ocular inflammation in the absence of CMV DNA, and HHV-7 was not detected in any of the vitreous samples. HHV-6A, HHV-6B, and HHV-7 DNA are detectable in less than 2% of vitreous samples in patients with ocular inflammation.

Indexed as

DNA, ViralEye DiseasesHerpesvirus 6, HumanHerpesvirus 7, HumanHumansPolymerase Chain ReactionRoseolovirus InfectionsVitreous BodyDNA, Viral

Identifiers

PMID20419813
PMCPMC2938775
OpenAlexW2030549923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.