ArticleInternational ophthalmology2010
Clinical manifestations of adult tubulointerstitial nephritis and uveitis (TINU) syndrome.
Article in International ophthalmology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Renal outcomes in tubulointerstitial nephritis and uveitis (TINU) syndrome: a systematic review and meta-analysis.Journal of nephrology · 2023Pooled it
- Article
- Tubulointerstitial nephritis and uveitis post COVID-19 infection in an adult.BMJ case reports · 2025Article
- Tubulointerstitial nephritis and uveitis syndrome in an adolescent female: a case report.Journal of medical case reports · 2021Article
- Tubulointerstitial nephritis and uveitis syndrome in a female adult.BMJ case reports · 2019Article
- Tubulointerstitial Nephritis and Uveitis Syndrome in an Elderly Man: Case Report and Literature Review.Medicine · 2015Article
- A case of adult-onset tubulointerstitial nephritis and uveitis syndrome presenting with granulomatous panuveitis.Taiwan journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To describe the clinical manifestations and response to therapy of adult patients with tubulointerstitial nephritis and uveitis (TINU) syndrome and to provide suggested work-up and treatment. We retrospectively examined medical records of all adult patients suffering from TINU at Soroka University Medical Center (SUMC) over the past 15 years. Characteristics of ocular and nephrologic manifestations were investigated with particular attention given to age, presenting signs and symptoms, treatment and course of disease. Five adult patients (median age 44 years) were diagnosed with TINU syndrome and followed from 1991-2006 at SUMC. As renal involvement was present at initial evaluation in all patients, they were all treated with steroids. They all suffered from moderate to severe ocular inflammation and most of them relapsed; they also suffered from TINU-related non-specific symptoms. The uveitis in our adult patients was more severe than previously reported. Renal failure and TINU-related non-specific symptoms were observed in all patients and led to the diagnosis of TINU and to systemic therapy which is more aggressive than the usual therapy for uvetis. Thus, early suspicion and diagnosis of TINU may help to direct the appropriate therapy for the degree of uveitis observed in these patients.
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