ArticlePloS one2010
Rapid and sensitive detection of rotavirus molecular signatures using surface enhanced Raman spectroscopy.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 106 citations in OpenAlex.
- Surface-Enhanced Raman Spectroscopy for Viral Diagnostics: Principles, Strategies, Clinical Challenges, and Future Directions.Chemical reviews · 2026Review
- Rapid preliminary screening of Tomato brown rugose fruit virus based on surface-enhanced Raman spectroscopy and machine learning.Frontiers in plant science · 2026Article
- Overcoming Challenges in Avian Influenza Diagnosis: The Role of Surface-Enhanced Raman Spectroscopy in Poultry Health Monitoring.Veterinary sciences · 2025Review
- Development and Evaluation of a Nanoparticle-Based Immunoassay for Rotavirus Detection: A Suitable Alternative to ELISA and PCR in Low-Income Setting.Methods and protocols · 2025Article
- Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids.mSystems · 2025Article
- Recent Advances in Molecular and Immunological Diagnostic Platform for Virus Detection: A Review.Biosensors · 2023Review
- Raman spectroscopy for viral diagnostics.Biophysical reviews · 2023Review
- Rapid Identification of Benign Gallbladder Diseases Using Serum Surface-Enhanced Raman Spectroscopy Combined with Multivariate Statistical Analysis.Diagnostics (Basel, Switzerland) · 2023Article
- Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors.Biosensors · 2022Review
- Advancements in Testing Strategies for COVID-19.Biosensors · 2022Review
- Molecular detection of bacterial contamination in plasma using magnetic-based enrichment.Scientific reports · 2022Article
- From Research to Diagnostic Application of Raman Spectroscopy in Neurosciences: Past and Perspectives.Free neuropathology · 2022Article
- Plasmonic Metasurfaces Based on Pyramidal Nanoholes for High-Efficiency SERS Biosensing.ACS applied materials & interfaces · 2021Article
- In situ food-borne pathogen sensors in a nanoconfined space by surface enhanced Raman scattering.Mikrochimica acta · 2021Review
- Onsite real-time detection of covid-like-virus transmission through air using spark-induced plasma spectroscopy.The Science of the total environment · 2021Article
- In Search of Spectroscopic Signatures of Periodontitis: A SERS-Based Magnetomicrofluidic Sensor for Detection ofACS sensors · 2021Article
- Rapid and sensitive detection of rotavirus by surface-enhanced Raman scattering immunochromatography.Mikrochimica acta · 2021Article
- TemporalACS omega · 2020Article
- SERS-Based Biosensors for Virus Determination with Oligonucleotides as Recognition Elements.International journal of molecular sciences · 2020Review
- A Survey of Analytical Techniques for Noroviruses.Foods (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human enteric virus infections range from gastroenteritis to life threatening diseases such as myocarditis and aseptic meningitis. Rotavirus is one of the most common enteric agents and mortality associated with infection can be very significant in developing countries. Most enteric viruses produce diseases that are not distinct from other pathogens, and current diagnostics is limited in breadth and sensitivity required to advance virus detection schemes for disease intervention strategies. A spectroscopic assay based on surface enhanced Raman scattering (SERS) has been developed for rapid and sensitive detection of rotavirus. The SERS method relies on the fabrication of silver nanorod array substrates that are extremely SERS-active allowing for direct structural characterization of viruses. SERS spectra for eight rotavirus strains were analyzed to qualitatively identify rotaviruses and to classify each according to G and P genotype and strain with >96% accuracy, and a quantitative model based on partial least squares regression analysis was evaluated. This novel SERS-based virus detection method shows that SERS can be used to identify spectral fingerprints of human rotaviruses, and suggests that this detection method can be used for pathogen detection central to human health care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.