ArticleBMJ (Clinical research ed.)2010
Estimating the population impact of screening strategies for identifying and treating people at high risk of cardiovascular disease: modelling study.
Article in BMJ (Clinical research ed.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guideline
- Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2016Pooled it
- Screening for increased cardiometabolic risk in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014Pooled it
- Population impact of a high cardiovascular risk management program delivered by village doctors in rural China: design and rationale of a large, cluster-randomized controlled trial.BMC public health · 2014Trial
- Comparing the effectiveness of two cardiovascular prevention programmes for highly educated professionals in general practice: a randomised clinical trial.BMC cardiovascular disorders · 2013Trial
- Mixed methods evaluation of targeted case finding for cardiovascular disease prevention using a stepped wedged cluster RCT.BMC public health · 2012Trial
- Guideline-Based Cardiovascular Risk Assessment Delivered by an mHealth App: Development Study.JMIR cardio · 2023Article
- Exploring targeted preventive health check interventions - a realist synthesis.BMC public health · 2023Review
- Article
- Prioritising cardiovascular disease risk assessment to high risk individuals based on primary care records.PloS one · 2023Article
- A cost-effectiveness analysis of risk-based intervention for prevention of cardiovascular diseases in IraPEN program: A modeling study.Frontiers in public health · 2023Article
- Article
- Mammographic features are associated with cardiometabolic disease risk and mortality.European heart journal · 2021Article
- Left Ventricular Hypertrophy in Diabetic Cardiomyopathy: A Target for Intervention.Frontiers in cardiovascular medicine · 2021Review
- Cost-effectiveness evaluation of the 45-49 year old health check versus usual care in Australian general practice: A modelling study.PloS one · 2018Article
- Review
- Treatment gaps and potential cardiovascular risk reduction from expanded statin use in the US and England.PloS one · 2018Article
- Participation in preventive health check-ups among 19,351 women in Germany.Preventive medicine reports · 2017Article
- 2016 European Guidelines on cardiovascular disease prevention in clinical practice : The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts).International journal of behavioral medicine · 2017Article
- The Role of Text Messaging in Cardiovascular Risk Factor Optimization.Current cardiology reports · 2017Review
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5 authors.
Funding
Abstract
objectiveTo estimate the potential population impact of different screening strategies for identifying and treating people at high risk of cardiovascular disease, including strategies using routine data for cardiovascular risk stratification, in light of the UK government's recommended national strategy to screen all adults aged 40-74 for cardiovascular risk.
designModelling study using data from a prospective cohort, EPIC-Norfolk (European Prospective Investigation of Cancer-Norfolk).
settingAn English county.
participants16,970 men and women aged 40-74 and free from cardiovascular disease and diabetes at baseline.
main outcome measuresThe main outcomes were the population attributable fraction, the number needed to screen to prevent one new case of cardiovascular disease, the number needed to treat to prevent one new case of cardiovascular disease, and the number of new cardiovascular events that could be prevented. Relative risk reductions for estimated treatment effects were derived from meta-analyses of clinical trials or guidelines from the National Institute for Health and Clinical Excellence.
results1362 cardiovascular events occurred over 183 586 person years of follow-up. Compared with the recommended government strategy, a stepwise screening approach using a simple risk score incorporating routine data could prevent a similar number (lower to upper estimates) of new cardiovascular events annually in the United Kingdom (26,789, 20,778 to 36,239) and 25,134 (19,450 to 34,134), respectively) but requiring only 60% of the population to be invited to attend a vascular risk assessment. A similar number of cardiovascular events (25,016, 19,563 to 33,372) could also be prevented by inviting everyone aged 50-74 for a vascular assessment. Using a participant completed Finnish diabetes risk score questionnaire or anthropometric cut-off points for risk prestratification was less effective.
conclusionsCompared with the UK government's recommended national strategy to screen all adults aged 40-74 for cardiovascular risk, an approach using routine data for cardiovascular risk stratification before inviting people at high risk for a vascular risk assessment may be similarly effective at preventing new cases of cardiovascular disease, with potential cost savings.
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