ArticleProceedings of the National Academy of Sciences of the United States of America2010
Two kinesin-like proteins mediate actin-based chloroplast movement in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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81 citing papers in PubMed, 162 citations in OpenAlex.
- Size of chloroplasts in Arabidopsis mesophyll cells affects jasmonate biosynthesis.Plant biology (Stuttgart, Germany) · 2026Article
- PERSPECTIVE: organelle positioning as a principle of metabolic regulation and stress tolerance.The Plant journal : for cell and molecular biology · 2026Review
- PEK14: A Kinesin-4 Necessary for Male-Derived Fertility in Arabidopsis thaliana.Cytoskeleton (Hoboken, N.J.) · 2026Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- Starch synthesis in Brachypodium distachyon endosperm occurs in dynamic, connected amyloplast compartments.The New phytologist · 2026Article
- RNAi reveals a unique set of kinesins mediating chloroplast motility in the giant cytoplasm of Bryopsis (Ulvophyceae), a coenocytic green alga.Journal of phycology · 2026Article
- Integrated genomic analysis of a diverse maize population reveals novel genes and superior predictive models for ear diameter.BMC genomics · 2025Article
- Optimal disk packing of chloroplasts in plant cells.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Membrane contact sites between chloroplasts and the pathogen interface underpin plant focal immune responses.The Plant cell · 2025Article
- Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems.BMC plant biology · 2025Article
- CHUP1 restricts chloroplast movement and effector-triggered immunity in epidermal cells.The New phytologist · 2024Article
- Strategies for adaptation to high light in plants.aBIOTECH · 2024Review
- Genome-Wide Association Study to Identify Possible Candidate Genes of Snap Bean Leaf and Pod Color.Genes · 2023Article
- FKF1 Interacts with CHUP1 and Regulates Chloroplast Movement in Arabidopsis.Plants (Basel, Switzerland) · 2023Article
- Formin protein DRT1 affects gross morphology and chloroplast relocation in rice.Plant physiology · 2023Article
- Article
- Regulation of alternative splicing by retrograde and light signals converges to control chloroplast proteins.Frontiers in plant science · 2023Article
- The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants.Stress biology · 2022Review
- The localization of PHRAGMOPLAST ORIENTING KINESIN1 at the division site depends on the microtubule-binding proteins TANGLED1 and AUXIN-INDUCED IN ROOT CULTURES9 in Arabidopsis.The Plant cell · 2022Article
- Light-induced displacement of PLASTID MOVEMENT IMPAIRED1 precedes light-dependent chloroplast movements.Plant physiology · 2022Article
21 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organelle movement is essential for efficient cellular function in eukaryotes. Chloroplast photorelocation movement is important for plant survival as well as for efficient photosynthesis. Chloroplast movement generally is actin dependent and mediated by blue light receptor phototropins. In Arabidopsis thaliana, phototropins mediate chloroplast movement by regulating short actin filaments on chloroplasts (cp-actin filaments), and the chloroplast outer envelope protein CHUP1 is necessary for cp-actin filament accumulation. However, other factors involved in cp-actin filament regulation during chloroplast movement remain to be determined. Here, we report that two kinesin-like proteins, KAC1 and KAC2, are essential for chloroplasts to move and anchor to the plasma membrane. A kac1 mutant showed severely impaired chloroplast accumulation and slow avoidance movement. A kac1kac2 double mutant completely lacked chloroplast photorelocation movement and showed detachment of chloroplasts from the plasma membrane. KAC motor domains are similar to those of the kinesin-14 subfamily (such as Ncd and Kar3) but do not have detectable microtubule-binding activity. The C-terminal domain of KAC1 could interact with F-actin in vitro. Instead of regulating microtubules, KAC proteins mediate chloroplast movement via cp-actin filaments. We conclude that plants have evolved a unique mechanism to regulate actin-based organelle movement using kinesin-like proteins.
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