Evidence map›Paper›PMID 20418086›Full record

ReviewCurrent opinion in cell biology2010

Structure and mechanism in membrane trafficking.

Frederick M Hughson, Karin M Reinisch

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Golgi inCOGnito: From vesicle tethering to human disease.Biochimica et biophysica acta. General subjects · 2020
    Review
  5. InducibleThe Journal of biological chemistry · 2019
    Article
  6. Exposing the Elusive Exocyst Structure.Trends in biochemical sciences · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The future of Golgi research.Molecular biology of the cell · 2010
    Article
  18. Article
  19. An update on transport vesicle tethering.Molecular membrane biology · 2010
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Frederick M HughsonDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. hughson@princeton.edu
Karin M Reinisch
Princeton University · USYale University · US

Funding

Structural Analysis of Membrane Tethering and Fusion ProteinsR01GM071574 · NIGMS · PRINCETON UNIVERSITY · PI HUGHSON, FREDERICK M · 2005 to 2024
$6.8M
Regulatory Mechanisms in Membrane TraffickingR01GM080616 · NIGMS · YALE UNIVERSITY · PI REINISCH, KARIN M · 2007 to 2018
$4.1M
NIGMS NIH HHS GM071574NIGMS NIH HHS GM080616NIGMS NIH HHS R01 GM071574NIGMS NIH HHS R01 GM080616
6 · The paper itself

Abstract

Cell biologists have long been interested in understanding the machinery that mediates movement of proteins and lipids between intracellular compartments. Much of this traffic is accomplished by vesicles (or other membranous carriers) that bud from one compartment and fuse with another. Given the pivotal roles that large protein complexes play in vesicular trafficking, many recent advances have relied on the combined use of X-ray crystallography and electron microscopy. Here, we discuss integrated structural studies of proteins whose assembly shapes membranes into vesicles and tubules, before turning to the so-called tethering factors that appear to orchestrate vesicle docking and fusion.

Indexed as

AnimalsBiological TransportCell MembraneCOP-Coated VesiclesHumansProtein Structure, TertiaryVesicular Transport ProteinsVesicular Transport Proteins

Identifiers

PMID20418086
PMCPMC2910180
OpenAlexW2072890475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.