ArticleInternational journal of oral and maxillofacial surgery2010
Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study.
Article in International journal of oral and maxillofacial surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 101 citations in OpenAlex.
- Effects of Ginkgo biloba extract on periodontal pathogens and its clinical efficacy as adjuvant treatment.Chinese journal of integrative medicine · 2014Trial
- One-pot fabrication and characterization of ZnO nanoflowers using Zanthoxylum simulans and evaluating their biomedical claims.Mikrochimica acta · 2026Article
- Exploring the phytochemical composition, ethnomedicinal uses, and therapeutic potential of Prunus species: a comprehensive review.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Efficacy and safety of Wuwei Xiaodu Drink in root canal therapy for chronic pulpitis: A retrospective cohort study.Medicine · 2026Article
- Process optimization of compound fermented traditional Chinese medicine and its feeding effect on dairy cows.AMB Express · 2026Article
- Inhibitory Effects of Phellodendri Cortex Against Airway Inflammation and Hyperresponsiveness in Ovalbumin-Induced Murine Asthma Model.Molecules (Basel, Switzerland) · 2025Article
- Effect of 13 traditional Chinese medicine drug preparations againstFrontiers in pharmacology · 2025Article
- Antibiotic Activity of Superior Class Traditional Chinese Medicine Herbs onmicroPublication biology · 2025Article
- Revealing the antimicrobial potential of traditional Chinese medicine through text mining and molecular computation.Briefings in bioinformatics · 2024Article
- Plant-Derived Compounds: A Promising Tool for Dental Caries Prevention.Current issues in molecular biology · 2024Review
- Evaluating the Effectiveness ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Effects of Tiaopi Xiezhuo decoction on constipation and gut dysbiosis in patients with peritoneal dialysis.Pharmaceutical biology · 2023Article
- Natural Medicine a Promising Candidate in Combating Microbial Biofilm.Antibiotics (Basel, Switzerland) · 2023Review
- The efficiency of natural wound healing and bacterial biofilm inhibition of Aloe vera and Sodium Chloride toothpaste preparation.BMC complementary medicine and therapies · 2022Article
- Antibiotic Discovery and Resistance: The Chase and the Race.Antibiotics (Basel, Switzerland) · 2022Review
- Antibiotic resistance modifying ability of phytoextracts in anthrax biological agent Bacillus anthracis and emerging superbugs: a review of synergistic mechanisms.Annals of clinical microbiology and antimicrobials · 2021Review
- Study on the mechanisms of the cross-resistance to TET, PIP, and GEN in Staphylococcus aureus mediated by the Rhizoma Coptidis extracts.The Journal of antibiotics · 2021Article
- Comprehensive Review of Phytochemical Constituents, Pharmacological Properties, and Clinical Applications ofFrontiers in pharmacology · 2021Review
- Assessment of the anti-virulence potential of extracts from four plants used in traditional Chinese medicine against multidrug-resistant pathogens.BMC complementary medicine and therapies · 2020Article
- Phellodendri Cortex: A Phytochemical, Pharmacological, and Pharmacokinetic Review.Evidence-based complementary and alternative medicine : eCAM · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twenty traditional Chinese medicines (TCM) were evaluated for their antimicrobial activity against four common oral bacteria. TCMs were tested for sensitivity against Streptococcus mitis, Streptococcus sanguis, Streptococcus mutans and Porphyromonas gingivalis. Aliquots of suspension of each bacterial species were inoculated onto a horse blood agar plate with TCMs soaked separately on 6mm paper disks. The plates were incubated for 48h anaerobically and the mean diameters of growth inhibition of three different areas obtained. 0.2% (w/v) chlorhexidine was used as a positive control. Broth microdilution assay was used to determine minimum inhibitory concentration and minimum bactericidal concentration. Fructus armeniaca mume was effective against all four bacteria. Thirteen TCMs demonstrated antimicrobial activity against Porphyromonas gingivalis, including Cortex magnoliae officinalis, Cortex phellodendri, Flos caryophylli, Flos lonicerae japonicae, Fructus armeniaca mume, Fructus forsythiae suspensae, Herba cum radice violae yedoensitis, Herba menthae haplocalycis, Pericarpium granati, Radix et rhizoma rhei, Radix gentianae, Ramulus cinnamomi cassia and Rhizoma cimicifugae. Cortex phellodendri showed antimicrobial activity against Streptococcus mutans, while Radix et rhizoma rhei was effective against Streptococcus mitis and Streptococcus sanguis. Fructus armeniaca mume had inhibitory effects against Streptococcus mitis, Streptococcus sanguis, Streptococcus mutans and Porphyromonas gingivalis in vitro.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.