ArticleNucleic acids research1991
Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Transcription factor Zfx regulates tumor's evasion to T cell killing in immunotherapy.iScience · 2025Article
- Maintenance of stem cell self-renewal by sex chromosomal zinc-finger transcription factors.World journal of methodology · 2024Article
- Generation of Transcript Length Variants and Reprogramming of mRNA Splicing During Atherosclerosis Progression in ApoE-Deficient Mice.Biomedicines · 2024Article
- Comparing the roles of sex chromosome-encoded protein homologs in gene regulation.Genes & development · 2024Review
- Sex chromosome-encoded protein homologs: current progress and open questions.Nature structural & molecular biology · 2024Review
- Dynamic Variations of 3'UTR Length Reprogram the mRNA Regulatory Landscape.Biomedicines · 2021Review
- Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.Nucleic acids research · 2020Article
- The Use of RNAi Technology to Interfere withBioMed research international · 2020Article
- RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.Mammalian genome : official journal of the International Mammalian Genome Society · 2017Article
- The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells.Stem cells (Dayton, Ohio) · 2014Article
- Knockdown of zinc finger protein X-linked inhibits prostate cancer cell proliferation and induces apoptosis by activating caspase-3 and caspase-9.Cancer gene therapy · 2012Article
- Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential.Human molecular genetics · 2012Article
- Knockdown of zinc finger protein, X-linked (ZFX) inhibits cell proliferation and induces apoptosis in human laryngeal squamous cell carcinoma.Molecular and cellular biochemistry · 2012Article
- An unusual arrangement of 13 zinc fingers in the vertebrate gene Z13.The Biochemical journal · 1995Article
- Complex genetic counseling and exclusion of Duchenne muscular dystrophy in a twin pregnancy after in vitro fertilization (IVF).Journal of assisted reproduction and genetics · 1994Article
- Potential problems in estimating the male-to-female mutation rate ratio from DNA sequence data.Journal of molecular evolution · 1993Article
- An X-linked zinc finger gene mapping to Xq21.1-q21.3 closely related to ZFX and ZFY: possible origins from a common ancestral gene.Nucleic acids research · 1991Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have cloned and sequenced transcripts from the X- and Y-linked zinc-finger genes ZFX and ZFY respectively and discuss a possible mechanism of post-transcriptional control by which these genes can be widely expressed but translated in only specific tissues. We report the identification of a novel 3'UTR (untranslated region) present in ZFY which is highly conserved among primates and contains a series of motifs implicated as mRNA instability determinants. These sequences can be substantially removed by polyadenylation directed from consensus (AATAAA) and non-consensus (AATATAAA) sequences in adult testis. The DNA-binding domains of the ZFY and ZFX proteins are compared using present models for zinc-finger/DNA interactions. Additionally, the genomic organisation of the ZFY coding sequence is presented as compared to that of ZFX.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.