ReviewClinical and experimental immunology2010
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: the role of infections in allergy: atopic asthma as a paradigm.
Review in Clinical and experimental immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Effects of antibiotic consumption on children 2-8 years of age developing asthma.Epidemiology and health · 2014Article
- Broadening the translational immunology landscape.Clinical and experimental immunology · 2012Article
- Dichlorophenol-containing pesticides and allergies: results from the US National Health and Nutrition Examination Survey 2005-2006.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2012Article
- Invariant NKT cells are required for airway inflammation induced by environmental antigens.The Journal of experimental medicine · 2011Article
- Antibiotic exposure by 6 months and asthma and allergy at 6 years: Findings in a cohort of 1,401 US children.American journal of epidemiology · 2011Article
- 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: lifestyle changes affecting the host-environment interface.Clinical and experimental immunology · 2010Article
- 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: symbionts and immunopathology in chronic diseases: insights from evolution.Clinical and experimental immunology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Earlier iterations of the 'hygiene hypothesis', in which infections during childhood protect against allergic disease by stimulation of the T helper type 2 (Th2)-antagonistic Th1 immunity, have been supplanted progressively by a broader understanding of the complexities of the underlying cellular and molecular interactions. Most notably, it is now clear that whole certain types of microbial exposure, in particular from normal gastrointestinal flora, may provide key signals driving postnatal development of immune competence, including mechanisms responsible for natural resistance to allergic sensitization. Other types of infections can exert converse effects and promote allergic disease. We review below recent findings relating to both sides of this complex picture.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.