ArticleThe Journal of infectious diseases2010
Human bocaviruses are highly diverse, dispersed, recombination prone, and prevalent in enteric infections.
Article in The Journal of infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
200 citing papers in PubMed, 2 syntheses or guidelines pooled it, 376 citations in OpenAlex.
- Prevalence of Human Bocavirus in Sewage, Surface Waters, and Other Environmental Milieux: A Meta-regression Modelling.Food and environmental virology · 2025Pooled it
- Risk of acute gastroenteritis associated with human bocavirus infection in children: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Human bocavirus in the nasopharynx of otitis-prone children.International journal of pediatric otorhinolaryngology · 2012Trial
- Trial
- Bat-Associated Parvoviruses: High Genetic Diversity and Novel Viruses in Gia Lai and Dong Nai Provinces, Vietnam.Viruses · 2026Article
- Respiratory Pathogen Detection Among Febrile Inpatients in Northern Tanzania, 2016-2019.Open forum infectious diseases · 2026Article
- Article
- Revealing the hidden burden: wastewater-based epidemiology for underreported and emerging infectious diseases in communities.Environmental monitoring and assessment · 2026Review
- Differential Interactions of Tissue-Restricted Host Proteins SPLUNC1 and VAMP8 with VP3 of Human Bocaviruses 1 and 2.Pathogens (Basel, Switzerland) · 2026Article
- Viral metagenomic analysis of human bocavirus in pediatric pneumonia: detection pattern and genetic characterization.Frontiers in cellular and infection microbiology · 2026Article
- Human bocavirus: As an emerging respiratory pathogen.World journal of virology · 2025Review
- Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate.Clinical microbiology reviews · 2025Review
- First Report of Human Bocavirus Genotypes 1-3 in Argentine Wastewater and Insights into Community Circulation.Food and environmental virology · 2025Article
- Genetic characteristics of human bocavirus in children with acute respiratory tract infections during 2023 in Beijing, China.Virology journal · 2025Article
- Prevalence and molecular characterization of human bocavirus in children with acute gastroenteritis in Beijing, China, during 2014-2023.Microbiology spectrum · 2025Article
- A Diagnostic Approach to Separate Acute Human Bocavirus 1 Respiratory Tract Infection From Long-lasting Virus Shedding.The Journal of infectious diseases · 2025Article
- The prevalence and genetic characteristics of human bocavirus in patients with acute respiratory infection in China during 2012-2021.Biosafety and health · 2025Article
- Molecular detection and characterization of human bocavirus in environmental waters in Thailand from 2020 to 2022.One health (Amsterdam, Netherlands) · 2025Article
- Article
- Human bocavirus infections in paediatric patients in a tertiary care hospital in Kerala, India.Archives of virology · 2025Article
140 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 7 institutions in 5 countries.
Funding
Abstract
A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4), was genetically characterized. Among 641 feces samples obtained from children and adults, the most commonly detected bocavirus species were, in descending order, HBoV2, HBoV3, HBoV4, and HBoV1, with an HBoV2 prevalence of 21% and 26% in Nigerian and Tunisian children, respectively. HBoV3 or HBoV4 species were found in 12 of 192 patients with non-polio acute flaccid paralysis in Tunisia and Nigeria and 0 of 96 healthy Tunisian contacts (P = .01). Evidence of extensive recombination at the NP1 and VP1 gene boundary between and within bocavirus species was found. The high degree of genetic diversity seen among the human bocaviruses found in feces specimens, relative to the highly homogeneous HBoV1, suggest that this worldwide-distributed respiratory pathogen may have recently evolved from an enteric bocavirus after acquiring an expanded tropism favoring the respiratory tract. Elucidating the possible role of the newly identified enteric bocaviruses in human diseases, including acute flaccid paralysis and diarrhea, will require further epidemiological studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.