Evidence map›Paper›PMID 20414762›Full record

GuidelineDer Anaesthesist2010

[Prevention, diagnosis, treatment, and follow-up care of sepsis. First revision of the S2k Guidelines of the German Sepsis Society (DSG) and the German Interdisciplinary Association for Intensive and Emergency Care Medicine (DIVI)].

K Reinhart, F M Brunkhorst, H-G Bone, J Bardutzky, C-E Dempfle, H Forst, P Gastmeier, H Gerlach, M Gründling, S John and 22 more

Registry-linked trialAbstract readGuideline
PubMed Publisher
In one paragraph

Guideline in Der Anaesthesist, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03334006 (Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03334006 phase2recruitingnot on this mapstarted 2017, after this paper: background citation

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

TypeinterventionalSponsorRWTH Aachen UniversityRan2017 to 2028Enrolled200ConditionsPeritonitis, Sepsis, Septic ShockArmsPentaglobin®/Standard of Care
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Observational
  7. Assessment of platelet biology in equine patients with systemic inflammatory response syndrome.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
  8. Observational
  9. Review
  10. Article
  11. Review
  12. Review
  13. [Updated definition of sepsis : Implications for diagnostics and therapy principles].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017
    Review
  14. Article
  15. Review
  16. [Rational use of antibiotics].Der Internist · 2016
    Review
  17. [Severe pneumonia in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2016
    Review
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

K ReinhartKlinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Jena der Friedrich-Schiller-Universität Jena, Erlanger Allee 101, 07747 Jena. Konrad.Reinhart@med.uni-jena.de
F M Brunkhorst
H-G Bone
J Bardutzky
C-E Dempfle
H Forst
P Gastmeier
H Gerlach
M Gründling
S John
W Kern
G Kreymann
W Krüger
P Kujath
G Marggraf
J Martin
K Mayer
A Meier-Hellmann
M Oppert
C Putensen
M Quintel
M Ragaller
R Rossaint
H Seifert
C Spies
F Stüber
N Weiler
A Weimann
K Werdan
T Welte
German Interdisciplinary Association for Intensive and Emergency Care Medicine
German Sepsis Society

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsAnti-Infective Agents, LocalDecontaminationFluid TherapyHemodynamicsHumansInfection ControlInfectionsMeningitis, BacterialPneumonia, Ventilator-AssociatedSepsisSurgical Wound InfectionTerminology as TopicAnti-Bacterial AgentsAnti-Infective Agents, Local

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.