ArticleWorld journal of emergency surgery : WJES2010
The role of pre-hospital blood gas analysis in trauma resuscitation.
Article in World journal of emergency surgery : WJES, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Optimizing Fluid Resuscitation Strategies: A Network Meta-analysis of Effectiveness and Safety for Hemorrhagic Shock Patients in Emergency Settings.The western journal of emergency medicine · 2025Pooled it
- Randomised controlled trials in pre-hospital trauma: a systematic mapping review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- The effectiveness of prehospital hypertonic saline for hypotensive trauma patients: a systematic review and meta-analysis.BMC emergency medicine · 2017Pooled it
- The acute management of trauma hemorrhage: a systematic review of randomized controlled trials.Critical care (London, England) · 2011Pooled it
- Diagnostic value of prehospital arterial blood gas measurements - a randomised controlled trial.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Trial
- [Prehospital cardiac arrhythmia-Is blood analysis the new gold standard?]Die Anaesthesiologie · 2025Article
- Effectiveness of road safety interventions: An evidence and gap map.Campbell systematic reviews · 2024Article
- Automatic real-time analysis and interpretation of arterial blood gas sample for Point-of-care testing: Clinical validation.PloS one · 2021Observational
- Relationship Between Initial Arterial Blood Gases and Coagulation Profiles - Analyzing the Prognosis and Outcomes in Patients with Multiple Injuries/Trauma.Open access emergency medicine : OAEM · 2020Article
- Point of care blood gases with electrolytes and lactates in adult emergencies.International journal of critical illness and injury science · 2014Article
- Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps.Shock (Augusta, Ga.) · 2014Article
- Polytrauma at the Emergency Department; can we relate arterial blood gas analysis to a shock classification?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2014Article
- [Point-of-care testing in preclinical emergency medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2014Review
- Intravenous Fluid Therapy in Traumatic Brain Injury and Decompressive Craniectomy.Bulletin of emergency and trauma · 2014Review
- Fluid therapy in neurotrauma: basic and clinical concepts.Reviews in health care · 2014Article
- Temperature and time stability of whole blood lactate: implications for feasibility of pre-hospital measurement.BMC research notes · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess, whether arterial blood gas measurements during trauma patient's pre-hospital shock resuscitation yield useful information on haemodynamic response to fluid resuscitation by comparing haemodynamic and blood gas variables in patients undergoing two different fluid resuscitation regimens.
methodsIn a prospective randomised study of 37 trauma patients at risk for severe hypovolaemia, arterial blood gas values were analyzed at the accident site and on admission to hospital. Patients were randomised to receive either conventional fluid therapy or 300 ml of hypertonic saline. The groups were compared for demographic, injury severity, physiological and outcome variables.
results37 patients were included. Mean (SD) Revised Trauma Score (RTS) was 7.3427 (0.98) and Injury Severity Score (ISS) 15.1 (11.7). Seventeen (46%) patients received hypertonic fluid resuscitation and 20 (54%) received conventional fluid therapy, with no significant differences between the groups concerning demographic data or outcome. Base excess (BE) values decreased significantly more within the hypertonic saline (HS) group compared to the conventional fluid therapy group (mean BE difference -2.1 mmol/l vs. -0.5 mmol/l, p = 0.003). The pH values on admission were significantly lower within the HS group (mean 7.31 vs. 7.40, p = 0.000). Haemoglobin levels were in both groups lower on admission compared with accident site. Lactate levels on admission did not differ significantly between the groups.
conclusionPre-hospital use of small-volume resuscitation led to significantly greater decrease of BE and pH values. A portable blood gas analyzer was found to be a useful tool in pre-hospital monitoring for trauma resuscitation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.