Trial reportPharmacotherapy2010
Effect of self-efficacy and social support on adherence to antihypertensive drugs.
Trial report in Pharmacotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Interventions for improving medication-taking ability and adherence in older adults prescribed multiple medications.The Cochrane database of systematic reviews · 2020Pooled it
- Pooled it
- Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014Pooled it
- Incorporating Patients' Social Determinants of Health into Hypertension and Depression Care: A Pilot Randomized Controlled Trial.Community mental health journal · 2017Trial
- Determinants of adherence to treatment in hypertensive patients of African descent and the role of culturally appropriate education.PloS one · 2015Trial
- Development and Validation of a Machine Learning Model for Predicting Medication Adherence Among Home-Dwelling Elderly Patients: A Retrospective Cross-Sectional Study.Patient preference and adherence · 2026Article
- Effectiveness of Pharmacist-Led Intervention on Medication Adherence in Chronic Diseases: A Systematic Review of Randomized Controlled Trials.Patient preference and adherence · 2025Review
- Factors influencing self-efficacy for self-management among adult people with human immune deficiency virus on antiretroviral therapy in public hospitals of south-west Ethiopia.Frontiers in psychology · 2024Article
- The mediating effect of self-efficacy on the relationship between social support and medication adherence in adults with type 2 diabetes.SAGE open medicine · 2024Article
- Dissemination of a telehealth cardiovascular risk service: The CVRS live protocol.Contemporary clinical trials · 2021Article
- Determining the Prevalence of and the Factors Associated with Antihypertensive Medication Non-Adherence in the Gaza Strip.Korean journal of family medicine · 2021Article
- The role of psychosocial determinants in predicting adherence to treatment in patient with hypertension.Interventional medicine & applied science · 2019Article
- Anticoagulation with Warfarin: Roles of Adherence, Social Support and Illness Perception.Innovations in pharmacy · 2019Article
- Updates to Adherence to Hypertension Medications.Current hypertension reports · 2018Review
- Impact of Gender on Satisfaction and Confidence in Cholesterol Control Among Veterans at Risk for Cardiovascular Disease.Journal of women's health (2002) · 2017Article
- The relationship between human dignity and medication adherence in patients with heart failure.Journal of medical ethics and history of medicine · 2017Article
- Avoiding Pitfalls With Implementation of Randomized Controlled Multicenter Trials: Strategies to Achieve Milestones.Journal of the American Heart Association · 2016Review
- Early Empowerment Strategies Boost Self-Efficacy to Improve Cardiovascular Health Behaviors.Global journal of health science · 2016Article
- The impact of patient support programs on adherence, clinical, humanistic, and economic patient outcomes: a targeted systematic review.Patient preference and adherence · 2016Review
- Correlates of Health-Related Quality of Life Among Korean Immigrant Elders.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2015Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectiveTo determine the relationship between poor adherence and self-efficacy or social support after a pharmacist intervention.
designPost-hoc analysis of data from two randomized controlled trials of physician-pharmacist collaborative interventions (6 and 9 mo, respectively) to improve blood pressure control.
settingEleven university-affiliated primary care clinics. PATIENTS: Five hundred eighty-four patients (aged 21-85 yrs) with uncontrolled primary hypertension; 296 were in the intervention group and 288 were in the control group.
interventionPharmacists provided intensified hypertension management and drug adherence counseling to patients in the intervention group. MEASUREMENTS AND MAIN
resultsSocial support and self-efficacy questionnaires were administered at baseline and end-of-study visits. Patient adherence was monitored by using the Morisky self-reported adherence questionnaire. Self-reported adherence scores improved significantly in the control group (p=0.0053) but not in the intervention group; however, adherence at baseline in both groups was high. There were small, but significant, improvements in self-efficacy (p<0.04) and social support (p<0.05) scores in the intervention group but not the control group at the end of the study. Social support and, to a lesser extent, self-efficacy improved as a function of duration of study participation (9-mo vs 6-mo intervention), regardless of whether the patient received the intervention. Blood pressure control in both groups improved significantly at the end of the study; however, mean blood pressure was significantly lower in the intervention group (129.7/76.6 mm Hg) compared with the control group (140.8/78.9 mm Hg; p<0.0001 for systolic, p=0.032 for diastolic).
conclusionSocial support and self-efficacy improved significantly in the intervention group at the end of the pharmacist intervention. Drug adherence was correlated with self-efficacy even though drug adherence did not improve significantly in the intervention group. The fact that social support and self-efficacy improved as a function of duration of study participation suggests that participation in a research study may have had a positive influence on these measures. Even though the changes in social support, self-efficacy, and drug adherence were modest, there was significantly better blood pressure control in the intervention group compared with the control group. These findings indicate that changes in drug adherence, self-efficacy, or social support probably played a minor role in the blood pressure outcomes in these studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.