ReviewInternational journal of impotence research
Vacuum therapy in erectile dysfunction--science and clinical evidence.
Review in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Pooled it
- The Early Use of Vacuum Therapy for Penile Rehabilitation After Radical Prostatectomy: Systematic Review and Meta-Analysis.American journal of men's health · 2018Pooled it
- Low intensity shockwave therapy in combination with phosphodiesterase-5 inhibitors is an effective and safe treatment option in patients with vasculogenic ED who are PDE5i non-responders: a multicenter single-arm clinical trial.International journal of impotence research · 2021Trial
- [Erectile dysfunction-It is time to act! : Practical tips and current guideline recommendations for diagnostics and treatment of a still underestimated disease].Urologie (Heidelberg, Germany) · 2026Article
- A Pragmatic Approach to Sexual Health in Movement Disorders.Movement disorders clinical practice · 2025Review
- Sexual function recovery following open and robotic radical prostatectomy: results of an academic penile rehabilitation program.Asian journal of andrology · 2025Article
- Atherosclerosis-induced arterial erectile dysfunction: pathogenesis, diagnosis, and therapeutic strategies.Translational andrology and urology · 2025Review
- Erectile Dysfunction in Diabetes Mellitus: A Comprehensive Narrative Review of Pathophysiology, Genetic Association Studies and Therapeutic Approaches.Endocrinology, diabetes & metabolism · 2025Review
- Patient Satisfaction and Outcomes of Penile Prosthesis Implantation in Psychogenic and Organic Erectile Dysfunction: A Comparative Study.Journal of clinical medicine · 2025Article
- The role of vacuum erection device and penile traction therapy in the patients after radical prostatectomy: a narrative review.International journal of impotence research · 2025Review
- Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025Review
- Simultaneous implant of inflatable penile prosthesis and artificial urinary sphincter: a single high-volume center experience.International journal of impotence research · 2025Article
- Vacuum erection device for erectile function rehabilitation after radical prostatectomy: which is the correct schedule? Results from a systematic, scoping review.International journal of impotence research · 2024Article
- Advanced hydrogels: New expectation for the repair of organic erectile dysfunction.Materials today. Bio · 2023Review
- Indications and characteristics of penile traction and vacuum erection devices.Nature reviews. Urology · 2022Review
- Advances in physical diagnosis and treatment of male erectile dysfunction.Frontiers in physiology · 2022Review
- Stem cell therapy and diabetic erectile dysfunction: A critical review.World journal of stem cells · 2021Review
- Prevalence of post-prostatectomy erectile dysfunction and a review of the recommended therapeutic modalities.International journal of impotence research · 2021Review
- Focusing on sexual rehabilitation besides penile rehabilitation following radical prostatectomy is important.International journal of impotence research · 2021Review
- Tissue response to applied loading using different designs of penile compression clamps.Medical devices (Auckland, N.Z.) · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vacuum therapy (VT) utilizes negative pressure to distend the corporal sinusoids and to increase the blood inflow to the penis. Depending on its purpose, VT could be used as vacuum constriction device (VCD), with the aid of an external constricting ring which is placed at the base of penis to prevent blood outflow, maintaining the erection for sexual intercourse. Also, as a vacuum erectile device (VED), without the application of a constriction ring, just increases blood oxygenation to the corpora cavernosa and for other purposes. The emerging of phosphodiesterase 5 inhibitors (PDE(5)I) for the treatment of erectile dysfunction (ED) eclipsed VCD as therapeutic choice for ED; however, widespread usage of VED as part of penile rehabilitation after radical prostatectomy and other purposes rekindle the interest for VT. The underlying hypothesis is that the artificial induction of erections shortly after surgery facilitates tissue oxygenation, reducing cavernosal fibrosis in the absence of nocturnal erections, and potentially increases the likelihood of preserving erectile function. Due to its ability to draw blood into the penis regardless of nerve disturbance, VED has become the centerpiece of penile rehabilitation protocols. Herein, we reviewed the history, mechanism, application, side effects and future direction of VT in ED.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.