Evidence map›Paper›PMID 20410726›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2010

Cognitive and psychiatric predictors to psychosis in velocardiofacial syndrome: a 3-year follow-up study.

Kevin M Antshel, Robert Shprintzen, Wanda Fremont, Anne Marie Higgins, Stephen V Faraone, Wendy R Kates

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 133 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Distinct neurocognitive profiles and clinical phenotypes associated with copy number variation at the 22q11.2 locus.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Psychiatric Comorbidities in Adults with DiGeorge Syndrome.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Specific differences in temporal binding aspects of the attentional blink in Chromosome 22q11.2 Deletion Syndrome.Cortex; a journal devoted to the study of the nervous system and behavior · 2018
    Article
  20. Childhood Executive Functioning Predicts Young Adult Outcomes in 22q11.2 Deletion Syndrome.Journal of the International Neuropsychological Society : JINS · 2018
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kevin M AntshelDepartment of Psychiatry and Behavioral Sciences, State University of New York-Upstate Medical University, Syracuse, NY 13210, USA. AntshelK@upstate.edu
Robert Shprintzen
Wanda Fremont
Anne Marie Higgins
Stephen V Faraone
Wendy R Kates
SUNY Upstate Medical University · US

Funding

Biomarkers for Psychosis in Velocardiofacial SyndromeR01MH064824 · NIMH · UPSTATE MEDICAL UNIVERSITY · PI KATES, WENDY · 2002 to 2015
$7.3M
Neuroanatomy and Cognition in Velocardiofacial SyndromeR01MH065481 · NIMH · UPSTATE MEDICAL UNIVERSITY · PI KATES, WENDY · 2003 to 2005
$816k
NIMH NIH HHS MH64824NIMH NIH HHS MH65481NIMH NIH HHS R01 MH064824NIMH NIH HHS R01 MH065481
6 · The paper itself

Abstract

objectiveTo predict prodromal psychosis in adolescents with velocardiofacial syndrome (VCFS).

methodA total of 70 youth with VCFS, 27 siblings of youth with VCFS, and 25 community controls were followed from childhood (mean age = 11.8 years) into mid-adolescence (mean age = 15.0 years). Psychological tests measuring intelligence, academic achievement, learning/memory, attention, and executive functioning as well as measures of parent and clinician ratings of child psychiatric functioning were completed at both time points.

resultsMajor depressive disorder, oppositional defiant disorder, and generalized anxiety disorder diagnoses increased in the VCFS sample. With very low false positive rates, the best predictor of adolescent prodromal psychotic symptoms was parent ratings of childhood odd/eccentric symptoms and child performance on a measure of executive functioning, the Wisconsin Card Sorting Test.

conclusionsSimilar to the non-VCFS prodromal psychosis literature, a combination of cognitive and psychiatric variables appears to predict psychosis in adolescence. A child with VCFS who screens positive is noteworthy and demands clinical attention.

Indexed as

CognitionPsychotic DisordersAdolescentAdolescent PsychiatryAnxiety DisordersAttentionAttention Deficit and Disruptive Behavior DisordersCausalityChildChild PsychiatryDiGeorge SyndromeEducational StatusExecutive FunctionFollow-Up StudiesHumansIntelligence

Identifiers

PMID20410726
PMCPMC2918883
OpenAlexW1969839453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.