Evidence map›Paper›PMID 20410711›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2010

Sex and age differences in attention-deficit/hyperactivity disorder symptoms and diagnoses: implications for DSM-V and ICD-11.

Ujjwal P Ramtekkar, Angela M Reiersen, Alexandre A Todorov, Richard D Todd

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 232 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
232citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

232 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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172 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ujjwal P RamtekkarWashington University in St Louis School of Medicine, Saint Louis, MO 63110, USA.
Angela M Reiersen
Alexandre A Todorov
Richard D Todd

Funding

Molecular Epidemiology of Inattentive ADHDR01MH067921 · NIMH · WASHINGTON UNIVERSITY · PI TODD, RICHARD D · 2004 to 2008
$4.4M
MOLECULAR BASIS OF SELECTED GXE EFFECTS IN COMBINED TYPE ADHDR01MH083823 · NIMH · WASHINGTON UNIVERSITY · PI TODOROV, ALEXANDRE A · 2008 to 2012
$3.3M
The Intersection of Autism and ADHDK08MH080287 · NIMH · WASHINGTON UNIVERSITY · PI REIERSEN, ANGELA M. · 2008 to 2012
$788k
NIMH NIH HHS K08 MH080287NIMH NIH HHS K08-MH-080287NIMH NIH HHS R01 MH067921NIMH NIH HHS R01-MH-067921NIMH NIH HHS R01 MH083823NIMH NIH HHS R01-MH-083823
6 · The paper itself

Abstract

objectiveTo examine gender and age differences in attention-deficit/hyperactivity disorder (ADHD) symptom endorsement in a large community-based sample.

methodFamilies with four or more full siblings ascertained from Missouri birth records completed telephone interviews regarding lifetime DSM-IV ADHD symptoms and the Strengths and Weaknesses of ADHD-Symptoms and Normal-behavior (SWAN) questionnaire for current ADHD symptoms. Complete data were available for 9,380 subjects aged 7 through 29 years. Lifetime and current DSM-IV-like ADHD diagnoses were assigned by the DSM-IV symptom criteria. Linear regression was used to examine sex and age effects on SWAN ADHD symptom scores. Logistic regression was used to examine sex and age effects on specific ADHD diagnoses. Fractional polynomial graphs were used to examine ADHD symptom count variations across age.

resultsOverall prevalence of current DSM-IV-like ADHD was 9.2% with a male:female ratio of 2.28:1. The prevalence of DSM-IV-like ADHD was highest in children. Gender differences in DSM-IV-like ADHD subtype prevalences were highest in adolescents. On average, individuals with lifetime DSM-IV-like ADHD diagnoses had elevated current ADHD symptoms even as adolescents or adults.

conclusionsLower male:female ratios than reported in some clinic-based studies suggest that females are underdiagnosed in the community. Although they may no longer meet the full symptom criteria, young adults with a history of lifetime DSM-IV-like ADHD maintain higher levels of ADHD symptoms compared with the general population. The use of age-specific diagnostic criteria should be considered for DSM-V and ICD-11.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersInternational Classification of DiseasesAdolescentAdultAge FactorsAttention Deficit Disorder with HyperactivityChildCohort StudiesCross-Sectional StudiesFemaleHealth SurveysHumansMaleMass ScreeningMissouriPersonality Assessment

Identifiers

PMID20410711
PMCPMC3101894

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.