ArticleJournal of clinical microbiology2010
Microsatellite typing to trace Aspergillus flavus infections in a hematology unit.
Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Review
- Short Tandem Repeat Genotyping of Medically Important Fungi: A Comprehensive Review of a Powerful Tool with Extensive Future Potential.Mycopathologia · 2024Review
- Structure of Aspergillus flavus populations associated with maize in Greece, Spain, and Serbia: Implications for aflatoxin biocontrol on a regional scale.Environmental microbiology reports · 2024Article
- Aspergillus flavus genetic structure at a turkey farm.Veterinary medicine and science · 2023Article
- Identification of a clonal population of Aspergillus flavus by MALDI-TOF mass spectrometry using deep learning.Scientific reports · 2022Article
- Distribution of active ingredients of a commercial aflatoxin biocontrol product in naturally occurring fungal communities across Kenya.Microbial biotechnology · 2021Article
- Invasive Aspergillosis byJournal of fungi (Basel, Switzerland) · 2019Review
- Challenges in Laboratory Detection of Fungal Pathogens in the Airways of Cystic Fibrosis Patients.Mycopathologia · 2018Article
- LC-MS/MS Tandem Mass Spectrometry for Analysis of Phenolic Compounds and Pentacyclic Triterpenes in Antifungal Extracts of Terminalia brownii (Fresen).Antibiotics (Basel, Switzerland) · 2017Article
- Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?Clinical microbiology reviews · 2017Review
- Microsatellite Typing of Aspergillus flavus Strains in a Tunisian Onco-hematology Unit.Mycopathologia · 2016Article
- Multilocus variable-number tandem-repeat analysis of clinical isolates of Aspergillus flavus from Iran reveals the first cases of Aspergillus minisclerotigenes associated with human infection.BMC infectious diseases · 2014Article
- Genetic structure of Aspergillus flavus populations in human and avian isolates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013Article
- Microsatellite typing of Aspergillus flavus from clinical and environmental avian isolates.Journal of medical microbiology · 2013Article
- Characterization of expressed sequence tag-derived simple sequence repeat markers for Aspergillus flavus: emphasis on variability of isolates from the southern United States.Mycopathologia · 2012Article
- Simple and highly discriminatory VNTR-based multiplex PCR for tracing sources of Aspergillus flavus isolates.PloS one · 2012Article
- Late post-operative Aspergillus flavus endocarditis: Demonstration of a six years incubation period using microsatellite typing.Medical mycology case reports · 2012Article
- A review molecular typing methods for Aspergillus flavus isolates.Mycopathologia · 2011Review
- High resolution genotyping of clinical Aspergillus flavus isolates from India using microsatellites.PloS one · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assessing the relatedness of strains isolated from patients and their environment is instrumental in documenting the source of preventable health care-associated life-threatening Aspergillus flavus human infection clusters. The present study aimed at identifying and selecting suitable microsatellite markers for A. flavus typing. This typing scheme was then applied to investigate the A. flavus epidemiology within a hematology unit in Sfax, Tunisia. Use of a combination of five markers made it possible to discern clusters of isolates and to substantiate the genetic diversity of A. flavus within clusters. Isolates from Tunisia and Marseille, France, displayed distinct haplotypes, indicating a highly significant geographical structuring of A. flavus. The typing of clinical and environmental A. flavus isolates in a hematology unit provided insights into its hospital epidemiology. From a heterogeneous genetic background, a cluster indicative of a clonal propagation episode within the unit could be identified. In two patients with invasive aspergillosis, the same genotype was found in clinical and environmental isolates, indicating hospital-acquired colonization and infection. In further studies, this novel microsatellite typing scheme might be instrumental in illuminating important epidemiological issues about A. flavus population genetics or epidemiology, including tracing the sources and routes of transmission.
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