Evidence map›Paper›PMID 20409426›Full record

ArticleJournal of studies on alcohol and drugs2010

Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence.

Sara L Simon, Andy C Dean, Xochitl Cordova, John R Monterosso, Edythe D London

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of studies on alcohol and drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 117 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Effect of modafinil on learning and task-related brain activity in methamphetamine-dependent and healthy individuals.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2011
    Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Methamphetamine dependence in Australia-why is 'ice' (crystal meth) so addictive?Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2024
    Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sara L SimonDepartment of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California 90095-1759, USA.
Andy C Dean
Xochitl Cordova
John R Monterosso
Edythe D London
University of California, Los Angeles · USUniversity of Southern California · US

Funding

NEUROCHEMISTRY OF MODAFINIL-MA INTERACTION IN RAT BRAINP20DA022539 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2006 to 2009
$2.9M
Neural Systems, Inhibitory Control, and Methamphetamine DependenceR01DA020726 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2005 to 2008
$2.0M
Early Methamphetamine Abstinence: fMRI and CognitionR01DA015179 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE D · 2003 to 2005
$1.4M
Expanding Access to Buprenorphine Treatment among Homeless Persons with Opioid Use DisorderR21DA050038 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MASSON, CARMEN L · 2020 to 2021
$446k
NIDA NIH HHS DA 020726NIDA NIH HHS DA 022539NIDA NIH HHS DA 15179NIDA NIH HHS DA 50038NIDA NIH HHS P20 DA022539NIDA NIH HHS R01 DA015179NIDA NIH HHS R01 DA020726NIDA NIH HHS R21 DA050038
6 · The paper itself

Abstract

objectiveThe purpose of this work was to assess neuropsychological functioning of individuals in early abstinence from methamphetamine dependence and to test for cognitive change over the first month of abstinence.

methodMethamphetamine-dependent subjects in very early abstinence from methamphetamine (4-9 days; n = 27) were compared with healthy comparison subjects (n = 28) on a test battery that evaluated five cognitive domains (attention/processing speed, learning/memory, working memory, timed executive functioning, and untimed executive functioning). A subsample of the methamphetamine-dependent subjects (n =18), who maintained abstinence for 1 month, as well as a subsample of the comparison subjects (n = 21), were retested.

resultsAt the first assessment, the methamphetamine-dependent subjects showed significantly worse performance than the comparison group on a test of processing speed; they also performed 0.31 SDs worse than the control group on a global battery composite score (p < .05). After a month of abstinence, methamphetamine-dependent subjects demonstrated slightly more cognitive improvement than healthy control subjects on the entire cognitive battery, but this difference did not approach statistical significance (p = .33).

conclusionsOur findings suggest that methamphetamine-dependent subjects do not show considerable cognitive gains in the first month of abstinence. A greater length of abstinence may be needed for cognitive improvement.

Indexed as

AdultAmphetamine-Related DisordersCase-Control StudiesCognition DisordersExecutive FunctionFemaleHumansLongitudinal StudiesMaleMemory DisordersMethamphetamineNeuropsychological TestsTime FactorsMethamphetamine

Identifiers

PMID20409426
PMCPMC2859784
OpenAlexW2094075971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.