ArticleAmerican journal of perinatology2010
Small for gestational age and higher birth weight predict childhood obesity in preterm infants.
Article in American journal of perinatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00059540 (The Maternal Lifestyle Study), which is not on this map. Cited by 37 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Maternal Lifestyle Study
Who cites it
37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The effects of different types of prenatal exercise on neonatal outcomes: a systematic review and network meta-analysis.Frontiers in physiology · 2026Pooled it
- Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy.PLoS genetics · 2020Pooled it
- Accelerated weight gain, prematurity, and the risk of childhood obesity: A meta-analysis and systematic review.PloS one · 2020Pooled it
- Does the association between early life growth and later obesity differ by race/ethnicity or socioeconomic status? A systematic review.Annals of epidemiology · 2017Pooled it
- Relationship between prenatal growth, postnatal growth and childhood obesity: a review.European journal of clinical nutrition · 2017Pooled it
- Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth.Human genetics · 2021Trial
- Infancy and Childhood Obesity Grade Predicts Weight Loss in Adulthood: The ONTIME Study.Nutrients · 2021Trial
- DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases.Clinical epigenetics · 2020Trial
- Development and external validation of an interpretable machine learning-based model for obesity risk prediction in 2-18-year-old children and adolescents in Beijing and Tangshan.Journal of global health · 2026Article
- Influence of Physical Activity during Pregnancy on Neonatal Complications: Systematic Review and Meta-Analysis.Journal of personalized medicine · 2023Review
- Association between prenatal socioeconomic disadvantage, adverse birth outcomes, and inflammatory response at birth.Psychoneuroendocrinology · 2023Article
- Growth During Infancy After Extremely Preterm Birth: Associations with Later Neurodevelopmental and Health Outcomes.The Journal of pediatrics · 2023Article
- Critical examination of relationships between early growth and childhood overweight in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Analysis of Factors Associated With Body Mass Index at Ages 18 and 36 Months Among Infants Born Extremely Preterm.JAMA network open · 2021Article
- Infant weight gain and DXA-measured adolescent adiposity: data from the Japan Kids Body-composition Study.Journal of physiological anthropology · 2021Article
- Fetal Programming Is Deeply Related to Maternal Selenium Status and Oxidative Balance; Experimental Offspring Health Repercussions.Nutrients · 2021Review
- Level of exercise and physical activity among pregnant women in Saudi Arabia: A systematic review.Journal of family medicine and primary care · 2021Review
- Temperament, socioeconomic adversity, and perinatal risk as related to preschoolers' BMI.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Article
- Associations between Diet Quality and Body Composition in Young Children Born with Very Low Body Weight.The Journal of nutrition · 2020Article
- Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
We sought to determine the association between small for gestational age (SGA), birth weight, and childhood obesity within preterm polysubstance exposed children. We sampled 312 preterm children with 11-year body mass index (BMI; age- and sex-specific) data from the Maternal Lifestyle Study (51% girls, 21.5% SGA, 46% prenatal cocaine, and 55% tobacco exposed). Multinomial regression analyzed the association between 11-year obesity (OBE) and overweight (OW) and SGA, birth weight, first-year growth velocity, diet, and physical activity variables. Overall, 24% were OBE (BMI for age ≥95th percentile) and 16.7% were OW (BMI ≥85th and <95th percentiles). In adjusted analyses, SGA was associated with OW (odds ratio [OR] = 3.4, confidence interval [CI] 1.5 to 7.5). Higher birth weight was associated with OBE (OR = 1.8, CI 1.3 to 2.4) and OW (OR = 1.4, CI 1.1 to 2.0). Growth velocity was associated with OBE (OR = 2.7, CI 1.8 to 4.0) and OW (OR = 1.6, CI 1.1 to 2.4). Low exercise was associated with OBE (OR = 2.1, CI 1.0 to 4.4) and OW (OR = 2.1, CI 1.0 to 4.5). There was no effect of substance exposure on obesity outcomes. Many (41%) of these high-risk preterm 11-year-olds were obese/overweight. Multiple growth-related processes may be involved in obesity risk for preterm children, including fetal programming as indicated by the SGA effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.