Evidence map›Paper›PMID 20407926›Full record

ArticlePharmacy world & science : PWS2010

Evaluating categorisation and clinical relevance of drug-related problems in medication reviews.

Anne Gerd Granas, Christian Berg, Vidar Hjellvik, Cecilie Haukereid, Arvid Kronstad, Hege S Blix, Bente Kilhovd, Kirsten K Viktil, Anne Marie Horn

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in Pharmacy world & science : PWS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. HIV pharmaceutical care in primary healthcare: Improvement in CD4 count and reduction in drug-related problems.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2017
    Article
  7. Review
  8. Pharmaceutical care in a long-stay psychiatric hospital.European journal of hospital pharmacy : science and practice · 2016
    Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Anne Gerd GranasDepartment of Public Health and Primary Health Care, Centre for Pharmacy, University of Bergen, Kalfarveien 31, 5018, Bergen, Norway. anne.granas@isf.uib.no
Christian Berg
Vidar Hjellvik
Cecilie Haukereid
Arvid Kronstad
Hege S Blix
Bente Kilhovd
Kirsten K Viktil
Anne Marie Horn
Norwegian Institute of Public Health · NOOslo University Hospital · NOUniversity of Bergen · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to evaluate the categorisation and clinical relevance of DRPs identified by community pharmacists, and further, to assess the quality of interventions with the patients and the physicians as documented by the pharmacists.

setting23 Norwegian community pharmacies.

methodPatients with type 2 diabetes were recruited by 24 community pharmacists who performed structured medication reviews based on the patients' drug profiles and patient interviews. The DRPs identified were subsequently categorised. An evaluation group (EG) retrospectively evaluated the reviews. Clinical/practical relevance of each DRP and quality of community pharmacists' intervention with patients and physician were scored. Average agreement between the EG and the community pharmacists was calculated. Internal agreement in the EG was calculated using a modified version of Fleiss' Kappa coefficient.

resultsA total of 73 patients were included (mean age 62 years, 52% female, on average prescribed 8.7 drugs). The pharmacists identified 88 DRPs in 43 of the patients. The most common DRPs were adverse drug reactions (22%) and wrong drug or dose used by patient (14%). Anti-diabetic drugs and lipid modifying drugs were associated with the most DRPs. The EG agreed with detection and categorisation of DRPs in more than 80% of the cases. The clinical/practical relevance of the detected DRPs was scored by the EG to be high or medium in 87% of the cases. The quality of the follow-up with patients and physicians was scored to be good or satisfactory in 93 and 98% of the cases, respectively.

conclusionsPre-defined categories of DRPs supported by structured forms were reliable and valid tools for identifying DRPs. The evaluation demonstrated that community pharmacists were able to identify DRPs of high to medium clinical/practical relevance, and to perform follow-ups of the DRPs with the patients and the physicians with a good or satisfactory quality.

Indexed as

Drug-Related Side Effects and Adverse ReactionsAgedCommunity Pharmacy ServicesDiabetes Mellitus, Type 2Drug Utilization ReviewFemaleHumansMaleMiddle AgedPharmacists

Identifiers

PMID20407926
OpenAlexW2118672645

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.