ArticleCirculation. Cardiovascular genetics2010
Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease.
Article in Circulation. Cardiovascular genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes.Scientific reports · 2016Pooled it
- Pooled it
- Trial
- Traditional cardiovascular risk factors explain the minority of the variability in carotid plaque.Stroke · 2012Trial
- Identification of modifier gene variants overrepresented in familial hypomagnesemia with hypercalciuria and nephrocalcinosis patients with a more aggressive renal phenotype.PLoS genetics · 2025Article
- Rare Modifier Variants Alter the Severity of Cardiovascular Disease in Pseudoxanthoma Elasticum: Identification of Novel Candidate Modifier Genes and Disease Pathways Through Mixture of Effects Analysis.Frontiers in cell and developmental biology · 2021Article
- Extreme phenotypes approach to investigate host genetics and COVID-19 outcomes.Genetics and molecular biology · 2021Article
- Extreme Phenotype Approach Suggests Taste Transduction Pathway for Carotid Plaque in a Multi-Ethnic Cohort.Stroke · 2020Article
- Article
- The Genetic Architecture of High Bone Mass.Frontiers in endocrinology · 2020Review
- Observational
- Opportunities and Challenges for Genetic Studies of End-Stage Renal Disease in Canada.Canadian journal of kidney health and disease · 2018Review
- Article
- Features and risk factors of carotid atherosclerosis in a population with high stroke incidence in China.Oncotarget · 2017Article
- A genome-wide association study of essential hypertension in an Australian population using a DNA pooling approach.Molecular genetics and genomics : MGG · 2017Article
- Sex Differences in Prevalence of and Risk Factors for Carotid Plaque among Adults: A Population-based Cross-Sectional Study in Rural China.Scientific reports · 2016Article
- Genetics of Common Antipsychotic-Induced Adverse Effects.Molecular neuropsychiatry · 2016Review
- Current status of carotid ultrasound in atherosclerosis.Quantitative imaging in medicine and surgery · 2016Review
- Prioritization of family member sequencing for the detection of rare variants.BMC proceedings · 2016Article
- SVSI: fast and powerful set-valued system identification approach to identifying rare variants in sequencing studies for ordered categorical traits.Annals of human genetics · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.