ArticleThe Plant cell2010
Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network.
Article in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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Who cites it
94 citing papers in PubMed, 167 citations in OpenAlex.
- Article
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- Chemical Genetics with SP600125 Reveals That Mps1 Protein Kinase Works as a Regulatory Element in Post-embryonic Development of theACS omega · 2025Article
- The role of FRUITFULL controlling cell cycle during early flower development revealed by time-series snRNA-seq experiments.Genome biology · 2025Article
- Mitotic Disruption and Cytoskeletal Alterations Induced byInternational journal of molecular sciences · 2025Article
- Harnessing Apple Cell Suspension Cultures in Bioreactors for Triterpene Production: Transcriptomic Insights into Biomass and Triterpene Biosynthesis.International journal of molecular sciences · 2025Article
- Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective.Cell death & disease · 2024Article
- Functional characterization of D-type cyclins involved in cell division in rice.BMC plant biology · 2024Article
- Exploring the potential role of fourFrontiers in plant science · 2024Article
- The SIAMESE family of cell-cycle inhibitors in the response of plants to environmental stresses.Frontiers in plant science · 2024Review
- The interplay between cell wall integrity and cell cycle progression in plants.Plant molecular biology · 2023Review
- Modelling how plant cell-cycle progression leads to cell size regulation.PLoS computational biology · 2023Article
- Phase separation-based visualization of protein-protein interactions and kinase activities in plants.The Plant cell · 2023Article
- Same, same but different: Exploring Plasmodium cell division during liver stage development.PLoS pathogens · 2023Review
- Article
- Article
- Study on the interaction preference between CYCD subclass and CDK family members at the poplar genome level.Scientific reports · 2022Article
- Control of division in Chlamydomonas by cyclin B/CDKB1 and the anaphase-promoting complex.PLoS genetics · 2022Article
- Antagonistic modules regulate photosynthesis-associated nuclear genes via GOLDEN2-LIKE transcription factors.Plant physiology · 2022Article
- A common F-box gene regulates the leucine homeostasis of Medicago truncatula and Arabidopsis thaliana.Protoplasma · 2022Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As in other eukaryotes, cell division in plants is highly conserved and regulated by cyclin-dependent kinases (CDKs) that are themselves predominantly regulated at the posttranscriptional level by their association with proteins such as cyclins. Although over the last years the knowledge of the plant cell cycle has considerably increased, little is known on the assembly and regulation of the different CDK complexes. To map protein-protein interactions between core cell cycle proteins of Arabidopsis thaliana, a binary protein-protein interactome network was generated using two complementary high-throughput interaction assays, yeast two-hybrid and bimolecular fluorescence complementation. Pairwise interactions among 58 core cell cycle proteins were tested, resulting in 357 interactions, of which 293 have not been reported before. Integration of the binary interaction results with cell cycle phase-dependent expression information and localization data allowed the construction of a dynamic interaction network. The obtained interaction map constitutes a framework for further in-depth analysis of the cell cycle machinery.
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