ArticlePsychological medicine2011
A population-based twin study of the genetic and environmental relationship of major depression, regular tobacco use and nicotine dependence.
Article in Psychological medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Relationship Between Secondhand Smoke Exposure and Depressive Symptoms: A Systematic Review and Dose⁻Response Meta-Analysis.International journal of environmental research and public health · 2019Pooled it
- Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.Biological psychiatry · 2015Pooled it
- Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive behavior in Prader-Willi syndrome.Molecular psychiatry · 2024Article
- Familial effects account for association between chronic pain and past month smoking.European journal of pain (London, England) · 2024Article
- Family history of depression is associated with alterations in task-dependent connectivity between the cerebellum and ventromedial prefrontal cortex.Depression and anxiety · 2021Article
- The Influence of Negative Mental Health on the Health Behavior and the Mortality Risk: Analysis of Korean Longitudinal Study of Aging from 2006 to 2014.Korean journal of family medicine · 2019Article
- Common genetic contributions to high-risk trauma exposure and self-injurious thoughts and behaviors.Psychological medicine · 2019Article
- Work Stress and Depressive Symptoms in Fishermen With a Smoking Habit: A Mediator Role of Nicotine Dependence and Possible Moderator Role of Expressive Suppression and Cognitive Reappraisal.Frontiers in psychology · 2018Article
- Biological underpinnings of an internalizing pathway to alcohol, cigarette, and marijuana use.Journal of abnormal psychology · 2018Article
- Shared familial risk between bulimic symptoms and alcohol involvement during adolescence.Journal of abnormal psychology · 2017Article
- Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism.Journal of affective disorders · 2017Article
- A Latent Class Analysis of Smokeless Tobacco Use in the United States.Journal of community health · 2016Article
- Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype.Psychological medicine · 2016Article
- Testing Causal Effects of Maternal Smoking During Pregnancy on Offspring's Externalizing and Internalizing Behavior.Behavior genetics · 2016Article
- Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement.Frontiers in genetics · 2016Article
- A Review of Impact of Tobacco Use on Patients with Co-occurring Psychiatric Disorders.Tobacco use insights · 2016Review
- Depression and the Risk of Peptic Ulcer Disease: A Nationwide Population-Based Study.Medicine · 2015Observational
- The pharmacogenetics of alcohol use disorder.Alcoholism, clinical and experimental research · 2015Review
- Depression and nicotine dependence from adolescence to young adulthood.Addictive behaviors · 2015Article
- Tobacco retailer proximity and density and nicotine dependence among smokers with serious mental illness.American journal of public health · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundNumerous epidemiological studies have reported a positive association between major depression (MD) and regular tobacco use (RU) or nicotine dependence (ND). However, few have used a genetically informative design to assess whether these traits share a common genetic and/or environmental liability.
methodWe assessed MD, RU and ND in same-sex twins from the population-based Swedish Twin Registry. In males, we examined both cigarette use and snus (smokeless tobacco) use. We used structural equation modeling to examine the relationship between MD, RU, and ND given RU.
resultsThe results suggest modest correlations between MD and RU, and between MD and ND. In males, the liability shared between MD and RU is solely genetic for both cigarettes and snus, while MD and ND share both genetic and unique environmental influences. The continuation to ND given RU differed considerably between cigarette and snus users. In females, both MD-RU and MD-ND relationships are partially attributable to genetic and unique environmental correlations.
conclusionsThe relationship among MD, RU and ND is at least partially attributable to shared genetic and environmental risk factors. The genetic and environmental correlations between traits are modest. The nature of the shared liability differs by sex, and in males, by the type of tobacco product used. Differences between previous reports and results presented in the current study are suggestive of population differences in how MD and tobacco use inter-relate.
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