Evidence map›Paper›PMID 20406476›Full record

SynthesisBMC public health2010

Exercise and global well-being in community-dwelling adults with fibromyalgia: a systematic review with meta-analysis.

George A Kelley, Kristi S Kelley, Jennifer M Hootman, Dina L Jones

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  9. Article
  10. Pain catastrophizing mediates the negative influence of pain and trait-anxiety on health-related quality of life in fibromyalgia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  11. Article
  12. Independent and combined association of overall physical fitness and subjective well-being with fibromyalgia severity: the al-Ándalus project.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015
    Article
  13. Physical exercise as non-pharmacological treatment of chronic pain: Why and when.Best practice & research. Clinical rheumatology · 2015
    Review
  14. Article
  15. Article
  16. Article
  17. Effect of milnacipran on body weight in patients with fibromyalgia.International journal of general medicine · 2012
    Article
  18. Exercise therapy for fibromyalgia.Current pain and headache reports · 2011
    Review
  19. Management strategies for fibromyalgia.Open access rheumatology : research and reviews · 2011
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

George A KelleyDepartment of Community Medicine, West Virginia University, Morgantown, West Virginia, USA. gkelley@hsc.wvu.edu
Kristi S Kelley
Jennifer M Hootman
Dina L Jones

Funding

PHS HHS U36/CCU319276
6 · The paper itself

Abstract

backgroundExercise has been recommended for improving global-well being in adults with fibromyalgia. However, no meta-analysis has determined the effects of exercise on global well-being using a single instrument and when analyzed separately according to intention-to-treat and per-protocol analyses. The purpose of this study was to fill that gap.

methodsStudies were derived from six electronic sources, cross-referencing from retrieved studies and expert review. Dual selection of randomized controlled exercise training studies published between January 1, 1980 and January 1, 2008 and in which global well-being was assessed using the Fibromyalgia Impact Questionnaire (FIQ) were included. Dual abstraction of data for study, subject and exercise program characteristics as well as assessment of changes in global well-being using the total score from the FIQ was conducted. Risk of bias was assessed using the Cochrane bias assessment tool. Random-effects models and Hedge's standardized effect size (g) were used to pool results according to per-protocol and intention-to-treat analyses.

resultsOf 1,025 studies screened, 7 representing 5 per-protocol and 5 intention-to-treat outcomes in 473 (280 exercise, 193 control) primarily female (99%) participants 18-73 years of age were included. Small, statistically significant improvements in global well-being were observed for per-protocol (g and 95% confidence interval, -0.39, -0.69 to -0.08) and intention-to-treat (-0.34, -0.53 to -0.14) analyses. No statistically significant within-group heterogeneity was found (per-protocol, Qw = 6.04, p = 0.20, I2 = 33.8%; intention-to-treat, Qw = 3.19, p = 0.53, I2 = 0%) and no between-group differences for per-protocol and intention-to-treat outcomes were observed (Qb = 0.07, p = 0.80). Changes were equivalent to improvements of 8.2% for per-protocol analyses and 7.3% for intention-to-treat analyses.

conclusionsThe results of this study suggest that exercise improves global well-being in community-dwelling women with fibromyalgia. However, additional research on this topic is needed, including research in men as well as optimal exercise programs for improving global well-being in adults.

Indexed as

Exercise TherapyHealth StatusAdultFemaleFibromyalgiaHumansIntention to Treat AnalysisMaleResidence Characteristics

Identifiers

PMID20406476
PMCPMC2874776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.