Evidence map›Paper›PMID 20405961›Full record

ArticleThe journal of physical chemistry. B2010

Applications of atomic force microscopy in biophysical chemistry of cells.

Zhao Deng, Valentin Lulevich, Fu-tong Liu, Gang-yu Liu

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. PeakForce Tapping resolves individual microvilli on living cells.Journal of molecular recognition : JMR · 2016
    Article
  6. Article
  7. The neuronal porosome complex in health and disease.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhao DengDepartment of Chemistry, University of California, Davis, Davis, California 95616, USA.
Valentin Lulevich
Fu-tong Liu
Gang-yu Liu
University of California, Davis · US

Funding

Using Nanotechnology to Regulate Integrin Clustering and Tensin LocalizationR21GM077850 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LIU, GANG-YU · 2006 to 2008
$556k
NIGMS NIH HHS R21 GM077850NIGMS NIH HHS R21 GM077850-01
6 · The paper itself

Abstract

This article addresses the question of what information and new insights atomic force microscopy (AFM) provides that are of importance and relevance to cellular biophysical chemistry research. Three enabling aspects of AFM are discussed: (a) visualization of membrane structural features with nanometer resolution, such as microvilli, ridges, porosomes, lamellapodia, and filopodia; (b) revealing structural evolution associated with cellular signaling pathways by time-dependent and high-resolution imaging of the cellular membrane in correlation with intracellular components from simultaneous optical microscopy; and (c) qualitative and quantitative measurements of single cell mechanics by acquisition of force-deformation profiles and extraction of Young's moduli for the membrane as well as cytoskeleton. A future prospective of AFM is also presented.

Indexed as

Microscopy, Atomic ForceAnimalsBiophysicsCell MembraneHumansMast Cells

Identifiers

PMID20405961
PMCPMC3980964
OpenAlexW2004469361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.