Evidence map›Paper›PMID 20405852›Full record

ArticleOrganic letters2010

Cell-trappable fluorescent probes for nitric oxide visualization in living cells.

Michael D Pluth, Lindsey E McQuade, Stephen J Lippard

Abstract read
In one paragraph

Article in Organic letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. AnChemical science · 2017
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael D PluthDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Lindsey E McQuade
Stephen J Lippard

Funding

Fluorescence Sensing of NO: Development of Reversible Sensors Using Fe(III)F32GM085930 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI PLUTH, MICHAEL · 2008 to 2009
$76k
NIGMS NIH HHS 5 F32 GM085930NIGMS NIH HHS F32 GM085930
6 · The paper itself

Abstract

Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.

Indexed as

AnimalsCell LineCopperDextransEstersFluorescent DyesHydrogen-Ion ConcentrationMiceMolecular StructureNitric OxideOrganometallic CompoundsPolymersStereoisomerismCopperDextransEstersFluorescent DyesNitric OxideOrganometallic CompoundsPolymers

Identifiers

PMID20405852
PMCPMC2871341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.