ArticlePloS one2010
The importance of age dependent mortality and the extrinsic incubation period in models of mosquito-borne disease transmission and control.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Effects of Temperature Dependence in Mosquito Mortality on Simulated Chikungunya Virus Transmission.Viruses · 2025Article
- Determining mosquito age using surface-enhanced Raman spectroscopy and artificial neural networks: insights into the influence of origin and sex.Parasites & vectors · 2025Article
- Warmer temperature accelerates reproductive senescence in mosquitoes.Frontiers in physiology · 2025Article
- Sand flies and Toscana virus: Intra-vector infection dynamics and impact on Phlebotomus perniciosus life-history traits.PLoS neglected tropical diseases · 2024Article
- Estimating the effects of temperature on transmission of the human malaria parasite, Plasmodium falciparum.Nature communications · 2024Article
- Mosquito ageing modulates the development, virulence and transmission potential of pathogens.Proceedings. Biological sciences · 2024Article
- Key considerations, target product profiles, and research gaps in the application of infrared spectroscopy and artificial intelligence for malaria surveillance and diagnosis.Malaria journal · 2023Review
- Occurrence of yellow fever outbreaks in a partially vaccinated population: An analysis of the effective reproduction number.PLoS neglected tropical diseases · 2022Article
- Omitting age-dependent mosquito mortality in malaria models underestimates the effectiveness of insecticide-treated nets.PLoS computational biology · 2022Article
- The effect of resource limitation on the temperature dependence of mosquito population fitness.Proceedings. Biological sciences · 2021Article
- Article
- Migration rate estimation in an epidemic network.Applied mathematical modelling · 2021Article
- Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potential.PLoS pathogens · 2020Article
- Effects of Mosquito Biology on Modeled Chikungunya Virus Invasion Potential in Florida.Viruses · 2020Article
- Age influences the thermal suitability ofProceedings. Biological sciences · 2020Article
- The Role of Vector Trait Variation in Vector-Borne Disease Dynamics.Frontiers in ecology and evolution · 2020Article
- Age-structured vectorial capacity reveals timing, not magnitude of within-mosquito dynamics is critical for arbovirus fitness assessment.Parasites & vectors · 2020Article
- New estimates of the Zika virus epidemic attack rate in Northeastern Brazil from 2015 to 2016: A modelling analysis based on Guillain-Barré Syndrome (GBS) surveillance data.PLoS neglected tropical diseases · 2020Article
- Quantifying the potential for bluetongue virus transmission in Danish cattle farms.Scientific reports · 2019Article
- Robustness of the reproductive number estimates in vector-borne disease systems.PLoS neglected tropical diseases · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Nearly all mathematical models of vector-borne diseases have assumed that vectors die at constant rates. However, recent empirical research suggests that mosquito mortality rates are frequently age dependent. This work develops a simple mathematical model to assess how relaxing the classical assumption of constant mortality affects the predicted effectiveness of anti-vectorial interventions. The effectiveness of mosquito control when mosquitoes die at age dependent rates was also compared across different extrinsic incubation periods. Compared to a more realistic age dependent model, constant mortality models overestimated the sensitivity of disease transmission to interventions that reduce mosquito survival. Interventions that reduce mosquito survival were also found to be slightly less effective when implemented in systems with shorter EIPs. Future transmission models that examine anti-vectorial interventions should incorporate realistic age dependent mortality rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.