ArticleMiddle East African journal of ophthalmology2009
Inflammatory choroidal neovascularization.
Article in Middle East African journal of ophthalmology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 55 citations in OpenAlex.
- EFFICACY AND SAFETY OF RANIBIZUMAB FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION DUE TO UNCOMMON CAUSE: Twelve-Month Results of the MINERVA Study.Retina (Philadelphia, Pa.) · 2018Trial
- Successful Management of Refractory toxoplasmosis-related Macular Neovascularization with Intravitreal Faricimab.Acta parasitologica · 2026Article
- Diagnostic Challenges in Inflammatory Choroidal Neovascularization.Medicina (Kaunas, Lithuania) · 2024Review
- OCT Angiography in Noninfectious Uveitis: A Description of Five Cases and Clinical Applications.Diagnostics (Basel, Switzerland) · 2023Article
- Morphological characterization of subretinal hyper-reflective material in posterior uveitis using swept-source optical coherence tomography and optical coherence tomography angiography.Indian journal of ophthalmology · 2022Observational
- Sarcoid Uveitis: An Intriguing Challenger.Medicina (Kaunas, Lithuania) · 2022Review
- Idiopathic multifocal choroiditis (MFC): aggressive and prolonged therapy with multiple immunosuppressive agents is needed to halt the progression of active disease. An offbeat review and a case series.Journal of ophthalmic inflammation and infection · 2022Review
- Simultaneous bilateral inflammatory choroidal neovascularization in a case of healed serpiginous-like choroiditis.GMS ophthalmology cases · 2022Article
- Serpiginous Choroiditis Complicated with Choroidal Neovascular Membrane Detected using Optical Coherence Tomography Angiography: A Case Series and Literature ReviewTurkish journal of ophthalmology · 2021Review
- Intravenous Immunoglobulin Treatment in Kawasaki Disease Decreases the Incidence of Myopia.Journal of clinical medicine · 2021Article
- Inflammatory Choroidal Neovascular Membranes in Patients With Noninfectious Uveitis: The Place of Intravitreal Anti-VEGF Therapy.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Review
- Optical coherence tomography angiography in unilateral multifocal choroiditis and panuveitis: A case report.Medicine · 2019Article
- An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management.Journal of ophthalmic inflammation and infection · 2018Review
- Intraocular DHODH-inhibitor PP-001 suppresses relapsing experimental uveitis and cytokine production of human lymphocytes, but not of RPE cells.Journal of neuroinflammation · 2018Article
- Inflammatory choroidal neovascularization in Indian eyes: Etiology, clinical features, and outcomes to anti-vascular endothelial growth factor.Indian journal of ophthalmology · 2017Article
- Choroidal neovascularisation as an unusual ophthalmic manifestation of cat-scratch disease in an 8-year-old girl.International ophthalmology · 2015Article
- Aflibercept for inflammatory choroidal neovascularization with persistent fluid on intravitreal ranibizumab therapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2014Article
- Risk of choroidal neovascularization among the uveitides.American journal of ophthalmology · 2013Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PURPOSE AND
methodsChoroidal neovascularization (CNV) can be a severe sight-threatening sequela, which can be secondary to both infectious and noninfectious uveitis. This review summarizes the different diseases associated with CNV, highlighting new treatment modalities and the possible strategies, which could be applied for the therapy of this occurrence.
resultsSince CNV can often originate from posterior pole lesions and can be hard to identify, an accurate examination is mandatory in order to identify the correct diagnosis. In the majority of cases, fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT) enable the determination of the clinical characteristics of the CNV. An infectious disease should be looked for to include a suitable therapy when available. The treatment strategy for CNV secondary to noninfectious uveal inflammations should be directed at controlling the inflammatory process. Systemic corticosteroids with or without immunosuppressive agents are indicated even when the CNV occurs with apparently inactive uveitis: Chronic subclinical inflammation can be the basis for the pathogenesis of CNV. Additional therapies aimed directly at the neovascular process, such as the intravitreal anti-Vascular Endothelial Growth Factor (VEGF) agents, are recommended particularly when the therapy shows an insufficient response.
conclusionCNV secondary to uveitis is a severe sequela leading to significant visual impairment. ICGA is mandatory in order to obtain relevant information about the choroidal status. Several therapeutic options have been considered, but no guidelines are provided at the moment. Moreover, the current data are still only based on case reports or small series. For such reasons, further trials are mandatory to validate the preliminary available results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.