Evidence map›Paper›PMID 20404840›Full record

ReviewNature reviews. Neuroscience2010

Branching out: mechanisms of dendritic arborization.

Yuh-Nung Jan, Lily Yeh Jan

Erratum issuedAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 415 papers.

0numbers the graph read from it
0cells of the map it votes in
415citing papers in PubMed
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

415 citing papers in PubMed, 714 citations in OpenAlex.

  1. Article
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  3. eLife · 2026
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  10. Concordant transcriptional and morphological remodeling revealed bybioRxiv : the preprint server for biology · 2026
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  13. The conserved fibroblast growth factor receptor-based signaling is required for dendrite regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  16. Review
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  18. Population Morphology Implies a Common Developmental Blueprint forbioRxiv : the preprint server for biology · 2025
    Article
  19. Article
  20. Article

355 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yuh-Nung JanHoward Hughes Medical Institute, Department of Physiology, University of California, 1550 4th Street, San Francisco 94158, USA. YuhNung.Jan@ucsf.edu
Lily Yeh Jan
Howard Hughes Medical Institute · USUniversity of California, San Francisco · US

Funding

Genetic Dissection of Dendrite DevelopmentR37NS040929 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, YUH NUNG · 2010 to 2016
$2.5M
Molecular mechanisms of dendrite development in mammalian CNSR01MH084234 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAN, YUH NUNG · 2008 to 2012
$1.7M
Howard Hughes Medical InstituteNIMH NIH HHS R01 MH084234NINDS NIH HHS R37 NS040929
6 · The paper itself

Abstract

Type-specific dendrite morphology is a hallmark of the neuron and has important functional implications in determining what signals a neuron receives and how these signals are integrated. During the past two decades, studies on dendritic arborization neurons in Drosophila melanogaster have started to identify mechanisms of dendrite morphogenesis that may have broad applicability to vertebrate species. Transcription factors, receptor-ligand interactions, various signalling pathways, local translational machinery, cytoskeletal elements, Golgi outposts and endosomes have been identified as contributors to the organization of dendrites of individual neurons and the placement of these dendrites in the neuronal circuitry. Further insight into these mechanisms will improve our understanding of how the nervous system functions and might help to identify the underlying causes of some neurological and neurodevelopmental disorders.

Indexed as

AnimalsAxonsDendritesHumansModels, NeurologicalMorphogenesisNeuronsSignal Transduction

Identifiers

PMID20404840
PMCPMC3079328
OpenAlexW2065943966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.