ArticlePlant signaling & behavior2010
The role of the transcript elongation factors FACT and HUB1 in leaf growth and the induction of flowering.
Article in Plant signaling & behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
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- Whole-genome resequencing reveals Brassica napus origin and genetic loci involved in its improvement.Nature communications · 2019Article
- araGWAB: Network-based boosting of genome-wide association studies in Arabidopsis thaliana.Scientific reports · 2018Article
- Identification of the Arabidopsis RAM/MOR signalling network: adding new regulatory players in plant stem cell maintenance and cell polarization.Annals of botany · 2015Article
- Major alterations in transcript profiles between C3-C4 and C4 photosynthesis of an amphibious species Eleocharis baldwinii.Plant molecular biology · 2014Article
- Monoubiquitination of histone 2B at the disease resistance gene locus regulates its expression and impacts immune responses in Arabidopsis.Plant physiology · 2014Article
- A duplicated NUCLEOLIN gene with antagonistic activity is required for chromatin organization of silent 45S rDNA in Arabidopsis.The Plant cell · 2014Article
- The role of FACT in making and breaking nucleosomes.Biochimica et biophysica acta · 2012Article
- Basic concepts of epigenetics: impact of environmental signals on gene expression.Epigenetics · 2012Review
- The predicted Arabidopsis interactome resource and network topology-based systems biology analyses.The Plant cell · 2011Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the cell nucleus, the packaging of the DNA into chromatin represses transcription by restricting the access of transcriptional regulators to their binding sites and inhibiting the progression of RNA polymerases during transcript elongation. To efficiently transcribe genes in the context of chromatin, eukaryotes have a variety of transcript elongation factors promoting transcription in vivo. The facilitates chromatin transcription (FACT) complex consisting of the SSRP1 and SPT16 proteins, is a histone chaperone that assists transcription by destabilising nucleosomes in the path of RNA polymerases. In a recent study, we report that Arabidopsis FACT is critically involved in different aspects of development including leaf growth and the transition to flowering. Moreover, FACT was found to interact genetically with HUB1 that mono-ubiquitinates histone H2B. Depending on the underlying process that is regulated by the two complexes, there appear to be different levels of interaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.