ArticleProceedings of the National Academy of Sciences of the United States of America2010
Sexual isolation of male moths explained by a single pheromone response QTL containing four receptor genes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed, 81 citations in OpenAlex.
- Ecological immunology: do sexual attraction and immunity trade-off through a desaturase?Insect science · 2025Article
- Evolution of queen pheromone receptor tuning in four honeybee species (Hymenoptera, Apidae, Apis).iScience · 2024Article
- Comparative analysis reveals assortative mate preferences in darters independent of sympatry and sex.Ecology and evolution · 2024Article
- Placing human gene families into their evolutionary context.Human genomics · 2022Review
- The Genetic Basis of Gene Expression Divergence in Antennae of Two Closely Related Moth Species,International journal of molecular sciences · 2022Article
- Evolution of the Sex Pheromone Communication System inInsects · 2021Review
- Article
- A single point mutation causes one-way alteration of pheromone receptor function in twoiScience · 2021Article
- bric à brac controls sex pheromone choice by male European corn borer moths.Nature communications · 2021Article
- Comparative dissection of the peripheral olfactory system of the Chagas disease vectors Rhodnius prolixus and Rhodnius brethesi.PLoS neglected tropical diseases · 2021Article
- Functional Characterization of Sex Pheromone Neurons and Receptors in the Armyworm,Frontiers in neuroanatomy · 2021Article
- Detection of heliothine sex pheromone components in the Australian budworm moth, Helicoverpa punctigera: electrophysiology, neuroanatomy, and behavior.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Article
- Visual mate preference evolution during butterfly speciation is linked to neural processing genes.Nature communications · 2020Article
- Evolution of olfactory circuits in insects.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Review
- An Orphan Pheromone Receptor Affects the Mating Behavior ofFrontiers in physiology · 2020Article
- Physical linkage and mate preference generate linkage disequilibrium for behavioral isolation in two parapatric crickets.Evolution; international journal of organic evolution · 2019Article
- Within-population variability in a moth sex pheromone blend, part 2: selection towards fixation.Royal Society open science · 2019Article
- Evolutionary ecology of chemosensation and its role in sensory drive.Current zoology · 2018Article
- Article
- The evolution of male mate choice and female ornamentation: a review of mathematical models.Current zoology · 2018Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long distance sexual communication in moths has fascinated biologists because of the complex, precise female pheromone signals and the extreme sensitivity of males to specific pheromone molecules. Progress has been made in identifying some genes involved in female pheromone production and in male response. However, we have lacked information on the genetic changes involved in evolutionary diversification of these mate-finding mechanisms that is critical to understanding speciation in moths and other taxa. We used a combined quantitative trait locus (QTL) and candidate gene approach to determine the genetic architecture of sexual isolation in males of two congeneric moths, Heliothis subflexa and Heliothis virescens. We report behavioral and neurophysiological evidence that differential male responses to three female-produced chemicals (Z9-14:Ald, Z9-16:Ald, Z11-16:OAc) that maintain sexual isolation of these species are all controlled by a single QTL containing at least four odorant receptor genes. It is not surprising that pheromone receptor differences could control H. subflexa and H. virescens responses to Z9-16:Ald and Z9-14:Ald, respectively. However, central rather than peripheral level control over the positive and negative responses of H. subflexa and H. virescens to Z11-16:OAc had been expected. Tight linkage of these receptor genes indicates that mutations altering male response to complex blends could be maintained in linkage disequilibrium and could affect the speciation process. Other candidate genes such as those coding for pheromone binding proteins did not map to this QTL, but there was some genetic evidence of a QTL for response to Z11-16:OH associated with a sensory neuron membrane protein gene.
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