ArticleRNA (New York, N.Y.)2010
Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.
Article in RNA (New York, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- N-Terminus of Cid14 Activates RNA Unwinding by Mtr4 in theBiochemistry · 2025Article
- Conserved Residues at the Mtr4 C-Terminus Coordinate Helicase Activity and Exosome Interactions.Biochemistry · 2024Article
- Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species.PLoS genetics · 2022Article
- RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response.Life science alliance · 2022Article
- RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe.Nucleic acids research · 2019Article
- H3K9 methylation extends across natural boundaries of heterochromatin in the absence of an HP1 protein.The EMBO journal · 2015Article
- Activation of the TOR Signalling Pathway by Glutamine Regulates Insect Fecundity.Scientific reports · 2015Article
- The RNA exosome promotes transcription termination of backtracked RNA polymerase II.Nature structural & molecular biology · 2014Article
- Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.RNA (New York, N.Y.) · 2014Article
- Ski2-like RNA helicase structures: common themes and complex assemblies.RNA biology · 2013Review
- The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression.Nucleic acids research · 2012Article
- Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation.Nucleic acids research · 2012Article
- Widespread cotranslational formation of protein complexes.PLoS genetics · 2011Article
- Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.The Journal of biological chemistry · 2011Article
- Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity.Wiley interdisciplinary reviews. RNAReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fission yeast Cid14 protein belongs to a family of noncanonical poly(A) polymerases which have been implicated in a broad range of biological functions. Here we describe an extensive Cid14 protein-protein interaction network and its biochemical dissection. Cid14 most stably interacts with the zinc-knuckle protein Air1 to form the Cid14-Air1 complex (CAC). Providing a link to ribosomal RNA processing, Cid14 sediments with 60S ribosomal subunits and copurifies with 60S assembly factors. In contrast, no physical link to chromatin has been identified, although gene expression profiling revealed that efficient silencing of a few heterochromatic genes depends on Cid14 and/or Air1.
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